Generating Compound-Protein Interaction Descriptors
Usage
getCPI(drugmat, protmat, type = c("combine", "tensorprod"))Arguments
- drugmat
The compound descriptor matrix.
- protmat
The protein descriptor matrix.
- type
The interaction type, one or two of
"combine"and"tensorprod".
Details
This function calculates the compound-protein interaction descriptors by three types of interaction:
combine- combine the two descriptor matrix, result has(p1 + p2)columnstensorprod- calculate column-by-column (pseudo)-tensor product type interactions, result has(p1 * p2)columns
See also
See getPPI for generating
protein-protein interaction descriptors.
Examples
x = matrix(1:10, ncol = 2)
y = matrix(1:15, ncol = 3)
getCPI(x, y, 'combine')
#> [,1] [,2] [,3] [,4] [,5]
#> [1,] 1 6 1 6 11
#> [2,] 2 7 2 7 12
#> [3,] 3 8 3 8 13
#> [4,] 4 9 4 9 14
#> [5,] 5 10 5 10 15
getCPI(x, y, 'tensorprod')
#> [,1] [,2] [,3] [,4] [,5] [,6]
#> [1,] 1 6 6 36 11 66
#> [2,] 4 14 14 49 24 84
#> [3,] 9 24 24 64 39 104
#> [4,] 16 36 36 81 56 126
#> [5,] 25 50 50 100 75 150
getCPI(x, y, type = c('combine', 'tensorprod'))
#> [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] [,10] [,11]
#> [1,] 1 6 1 6 11 1 6 6 36 11 66
#> [2,] 2 7 2 7 12 4 14 14 49 24 84
#> [3,] 3 8 3 8 13 9 24 24 64 39 104
#> [4,] 4 9 4 9 14 16 36 36 81 56 126
#> [5,] 5 10 5 10 15 25 50 50 100 75 150
getCPI(x, y, type = c('tensorprod', 'combine'))
#> [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] [,10] [,11]
#> [1,] 1 6 1 6 11 1 6 6 36 11 66
#> [2,] 2 7 2 7 12 4 14 14 49 24 84
#> [3,] 3 8 3 8 13 9 24 24 64 39 104
#> [4,] 4 9 4 9 14 16 36 36 81 56 126
#> [5,] 5 10 5 10 15 25 50 50 100 75 150