TargetNet


Q9ULX7

Carbonic anhydrase 14


Function

Reversible hydration of carbon dioxide.


Database Links

Database Links
UniProt Q9ULX7
PDB 4LU3
BioGrid 117162
BindingDB Q9ULX7
DrugBank Not available
Guide to PHARMACOLOGY 2598
PharmGKB PA25988
KEGG hsa:23632
BioCyc Not available
Entrez Gene (GeneID) 23632

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9711 0.0033
Accuracy 0.9221 0.0043
Sensitivity 0.9112 0.0078
Specificity 0.933 0.0041
BEDROC 0.9991 8.1995 × 10-4
MCC Threshold 0.432 N/A
MCC 0.8309 N/A
F-score Threshold 0.432 N/A
F-score 0.9161 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:53