TargetNet
Q9UKP6
Urotensin-2 receptor
Function
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | Q9UKP6 |
| PDB | Not available |
| BioGrid | 109097 |
| BindingDB | Q9UKP6 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 365 |
| PharmGKB | PA28857 |
| KEGG | hsa:2837 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 2837 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9749 | 0.0019 |
| Accuracy | 0.9357 | 0.0031 |
| Sensitivity | 0.9534 | 0.0069 |
| Specificity | 0.9147 | 0.0102 |
| BEDROC | 0.9697 | 0.0112 |
| MCC Threshold | 0.59 | N/A |
| MCC | 0.899 | N/A |
| F-score Threshold | 0.59 | N/A |
| F-score | 0.9526 | N/A |