TargetNet


Q9QZN9

Cannabinoid receptor 2


Function

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis (By similarity).


Database Links

Database Links
UniProt Q9QZN9
PDB Not available
BioGrid Not available
BindingDB Q9QZN9
DrugBank Not available
Guide to PHARMACOLOGY 57
PharmGKB Not available
KEGG rno:57302
BioCyc Not available
Entrez Gene (GeneID) 57302

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9168 0.0097
Accuracy 0.8634 0.0065
Sensitivity 0.8586 0.0094
Specificity 0.8689 0.0061
BEDROC 0.9912 0.0061
MCC Threshold 0.612 N/A
MCC 0.7736 N/A
F-score Threshold 0.538 N/A
F-score 0.8889 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:53