Histamine H3 receptor
The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist).
Database | Links |
---|---|
UniProt | Q9QYN8 |
PDB | Not available |
BioGrid | Not available |
BindingDB | Q9QYN8 |
DrugBank | Not available |
Guide to PHARMACOLOGY | 264 |
PharmGKB | Not available |
KEGG | rno:85268 |
BioCyc | Not available |
Entrez Gene (GeneID) | 85268 |
Metric | Mean Value | Standard Deviation |
---|---|---|
AUC | 0.9881 | 9.7016 × 10-4 |
Accuracy | 0.9624 | 0.0024 |
Sensitivity | 0.9733 | 0.0033 |
Specificity | 0.9495 | 0.0028 |
BEDROC | 0.9851 | 0.0054 |
MCC Threshold | 0.58 | N/A |
MCC | 0.9362 | N/A |
F-score Threshold | 0.58 | N/A |
F-score | 0.9705 | N/A |