TargetNet
Q99705
Melanin-concentrating hormone receptor 1
Function
Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.
Database Links
| Database | Links |
|---|---|
| UniProt | Q99705 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | Q99705 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 280 |
| PharmGKB | PA28867 |
| KEGG | hsa:2847 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 2847 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.987 | 4.8052 × 10-4 |
| Accuracy | 0.9561 | 0.0017 |
| Sensitivity | 0.9626 | 0.0022 |
| Specificity | 0.9501 | 0.0018 |
| BEDROC | 0.9911 | 0.0022 |
| MCC Threshold | 0.482 | N/A |
| MCC | 0.9145 | N/A |
| F-score Threshold | 0.482 | N/A |
| F-score | 0.9557 | N/A |