TargetNet


Q95323

Carbonic anhydrase 4


Function

Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity).


Database Links

Database Links
UniProt Q95323
PDB Not available
BioGrid Not available
BindingDB Q95323
DrugBank Not available
Guide to PHARMACOLOGY Not available
PharmGKB Not available
KEGG bta:280741
BioCyc Not available
Entrez Gene (GeneID) 280741

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9965 1.9176 × 10-4
Accuracy 0.9791 0.0016
Sensitivity 0.9872 0.0021
Specificity 0.9718 0.0022
BEDROC 0.9977 0.0016
MCC Threshold 0.554 N/A
MCC 0.9622 N/A
F-score Threshold 0.554 N/A
F-score 0.98 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:51