smile	binding.affinity
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	5.8
[H]C1=NC(OC2=C([H])C([H])=C(Br)C([H])=C2[H])=C(C(=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	50
[H]C1=NC(OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C(=O)OC([H])([H])[H])=C(C(=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	1000
[H]N(C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])N=C1[H]	400
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	1200
[H]C1=NN(C([H])=N1)C1=C([H])C([H])=C(OC2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])[N+]([O-])=O)C([H])=C1[H]	2500
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	12.4
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	4.7
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[N+]([O-])=O	24
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H])[N+]([O-])=O	660
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	1.5
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	160
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	227.5
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])[N+]([O-])=O)C([H])=C1[H]	3000
[H]C1=NC(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C(C(=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	1900
[H]C1=NC(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])=C(C(=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	1700
[H]C1=NC(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2[H])=C(C(=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	500
[H]C1=C(OC2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])[N+]([O-])=O)N(N=C1C(F)(F)F)C([H])([H])[H]	84
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	260
[H]N(C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O)C1=C(F)C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]	7.45
[H]N(C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O)C1=C(F)C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	0.665
[H]N(C1=C([H])C(F)=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	3.4
[H]N(C1=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	110
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)C([H])([H])C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O	17.1
[H]C1=NC(OC2=C(N=C([H])C([H])=C2[H])C([H])([H])[H])=C(C(O[C@]2([H])[C@@]3([H])OC([H])([H])[C@]2([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C3([H])[H])=N1)C([H])([H])[H]	1419
[H]C1=NC(OC2=C(N=C([H])C([H])=C2[H])C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	18.5
[H]C1=NC(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=C(C(O[C@]2([H])[C@@]3([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C3([H])[H])=N1)C([H])([H])[H]	2526.25
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	12.85
[H]C1=NN(C2=NC([H])=NC(N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	3.4
[H]C1=NN(C2=NC([H])=NC(=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	3.4
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	3.65
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	4.2
[H]C1=NN(C2=NC([H])=NC(SC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	5.6
[H]C1=NN(C2=NC([H])=NC(N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	8.95
[H]C1=NN(C2=NC([H])=NC(=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	7.3
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C2N=NN(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	7.4
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	7.5
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	8.1
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C2ON=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	14
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	14.6
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C2C(=N1)N(N=C2C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	15
[H]C1=NC2=C(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])N=C([H])N=C2N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	33.4
ON(=O)C1=C(N=CN=C1NC1=CC=C(C=C1)N1C=NC=N1)N1CCC(CC1)SC1=NC=CC=C1	130
[H]C1=C([H])C([H])=C(O1)C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=N2)C([H])([H])C1([H])[H]	1900
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]	2600
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]	800
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]	300
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]	100
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])OC([H])([H])[H]	300
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	200
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	90
[H]C1=NC([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=N2)C([H])([H])C1([H])[H]	2000
[H]C1=C([H])C([H])=C(S1)S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=N2)C([H])([H])C1([H])[H]	1800
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]	1200
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	1000
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]	1000
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]	1600
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]	800
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]	2800
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])(F)F)C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]	2100
[H]C1=C([H])C([H])=C(O1)C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]	2000
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	900
[H]C1=NC(=C([H])C([H])=C1OC1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]	2100
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]	1200
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]	700
[H]N(C(=O)C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1F)C([H])([H])[C@@]([H])(F)C1([H])C([H])([H])C([H])([H])N(C(=O)OC2(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]	730
[H]N(C(=O)C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1F)C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	13
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	884
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=NN=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	267
[H]N(C(=O)C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	75
[H]N(C(=O)C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	78
[H]N(C(=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	120
[H]N(C(=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	808
[H]N(C(=O)C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	340
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	5980
[H]N(C(=O)C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1F)C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	220.5
[H]N(C(=O)C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1F)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC2(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]	236
[H]C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	3600
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	1400
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	514
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	338
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]	22
[H]C1=C([H])C(=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	1900
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[S@](=O)C([H])([H])[H]	11
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)C([H])([H])[H]	25
[H]C1=C([H])C(=C([H])C([H])=C1SC([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	600
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	76
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	831
[H]C1=NN(C2=NC([H])=NC(N3C([H])([H])C([H])([H])C([H])(C4=NC(=NO4)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	42
[H]C1=C([H])C(=C([H])C([H])=C1N1N=C(C2=C(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])N=C(N=C12)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	116
[H]N(C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	250
[H]N(C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	265
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)O[C@@]4([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	435
[H]C1=NN(C2=NC([H])=NC(=C12)[S@](=O)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	6200
[H]C1=NN(C2=NC([H])=NC(SC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	0.5
[H]N1C(=O)N(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	0.6
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C2ON=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	0.7
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	0.9
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]	1.1
[H]C1=NC([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	116
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	526
[H]C1=C([H])N=C(C([H])=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	103
[H]C1=C([H])C(=NC(=N1)C#N)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	6
[H]C1=NC(C#N)=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	6
[H]C1=C(N=C(N=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C#N)C([H])([H])[H]	1
[H]C1=C(N=C(N=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C#N	2
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	39
[H]C1=NC([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	201
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	98
[H]C1=NC(=NC([H])=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	57
[H]C1=NC(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	48
[H]C1=NC(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	19
[H]C1=NC(=C([H])C([H])=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	18
[H]C1=NC(=C([H])C([H])=C1C#N)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	62
[H]C1=NC(=C([H])C([H])=C1C(F)(F)F)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	13
[H]C1=NC(=NC([H])=C1Cl)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	5
[H]C1=NC(=NC([H])=C1Cl)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NC(=C2[H])C([H])([H])[H])C#N)C([H])([H])C1([H])[H]	2
[H]C1=NC(=NC([H])=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NC(C#N)=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]	8
[H]C1=NC(=C([H])N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NC(C#N)=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]	30
[H]C1=NC(=C([H])N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NC(=C2[H])C([H])([H])[H])C#N)C([H])([H])C1([H])[H]	19
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])C([H])([H])[C@]2([H])C2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C(Cl)C([H])=N3)C([H])([H])C2([H])[H])C([H])=C1F)C1([H])C([H])([H])C1([H])[H]	11.5
[H]C1=NC(=NC([H])=C1Cl)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=N1)S(=O)(=O)C([H])([H])[H]	4
[H]C1=C([H])N(N=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]2([H])C2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C(Cl)C([H])=N3)C([H])([H])C2([H])[H])C([H])=C1[H]	4
[H]C1=C([H])N(N=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]2([H])C2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C(Cl)C([H])=N3)C([H])([H])C2([H])[H])N=C1[H]	2
[H]C1=NC(=NC([H])=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])OC1=NC(C#N)=C([H])C(=N1)C([H])([H])[H]	2
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	97
[H]C1=NC(OC2=C(F)C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1	82
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	131
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N(C(=O)OC4(C([H])([H])[H])C([H])([H])C4([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	18
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N(C(=O)OC([H])([H])C(F)(F)F)[C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	61
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N(C(=O)OC([H])([H])C4([H])C([H])([H])C4([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	37
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C([H])([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	330
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C([H])([H])C(F)(F)F)=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	112
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	24
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C(F)(F)F)=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	112
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	30
[H]C1=C(Cl)SC(=C1[H])S(=O)(=O)N1C2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]([H])(OC1=C(C(OC3=C([H])C([H])=C([H])N=C3C([H])([H])[H])=NC([H])=N1)C([H])([H])[H])C2([H])[H]	25
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	42
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C(F)(F)F)=N1)C([H])([H])[H]	2120
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	166
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])C([H])=C2Cl)=N1)C([H])([H])[H]	44
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])C([H])=C2C#N)=N1)C([H])([H])[H]	7
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C(Cl)C([H])=C2C#N)=N1)C([H])([H])[H]	50
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1C([H])([H])[H]	54
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C#N	86
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1C#N	34
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1F	15
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1Cl	3
[H]C1=C([H])[C@]2([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]([H])(OC1=C(C(OC3=C([H])C([H])=C([H])N=C3C([H])([H])[H])=NC([H])=N1)C([H])([H])[H])C2([H])[H]	18
[H]C1=C([H])[C@]2([H])N([C@@]1([H])C([H])([H])[C@@]([H])(OC1=C(C(OC3=C([H])C([H])=C([H])N=C3C([H])([H])[H])=NC([H])=N1)C([H])([H])[H])C2([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]	38
[H]O[C@]1([H])C([H])([H])[C@]2([H])N(C1([H])C([H])([H])[C@@]([H])(OC1=C(C(OC3=C([H])C([H])=C([H])N=C3C([H])([H])[H])=NC([H])=N1)C([H])([H])[H])C2([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]	1150
[H]C1=NC(O[C@@]2([H])C([H])([H])[C@@]3([H])N(C([H])(C2([H])[H])[C@]([H])(F)C3([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	130
[H]C1=NC(O[C@]2([H])C([H])([H])[C@]3([H])N([C@@]([H])(C([H])([H])C3=O)C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	918
[H]C1=NC(O[C@@]2([H])C([H])([H])C3([H])N([C@]([H])(C2([H])[H])C(F)(F)C3([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	62
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]	5000
[H]C1=NC(OC2=C(N=C([H])C([H])=C2[H])C([H])([H])[H])=C(C(O[C@]2([H])C([H])([H])[C@]3([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]2([H])C3([H])[H])=N1)C([H])([H])[H]	709
[H]OC([H])([H])C([H])([H])N([H])C1=NC(=NC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]	2500
[H]N(C1=C([H])C([H])=C(N=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H]	1000
[H]C1=NC(OC2=C(C([H])=C(N=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	60
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H])C1=C(C([H])=C(N=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]	250
[H]C1=NC(OC2=C([H])C([H])=NC([H])=C2C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	5000
[H]N(C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	2330
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	50
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	60
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])(F)F)C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	47
[H]OC([H])([H])C1=C(N=C([H])N=C1OC1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	1100
[H]N(C1=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	46
[H]N(C1=C(OC([H])([H])C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	57.5
[H]OC1=C(N=C([H])N=C1OC1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	1320
[H]N(C1=C(OC([H])(F)F)C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	115
[H]N(C1=C(C#N)C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	120
[H]N(C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(N=C1[N+]([O-])=O)S(=O)(=O)C([H])([H])[H]	1410
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1C([H])([H])[H]	92
[H]N(C1=C([H])C([H])=C(C(=N1)C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H]	475
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	34
[H]N(C1=C(C([H])=C(C([H])=N1)S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H]	235
[H]C1=NC(OC2=C([H])C([H])=C(C([H])=C2F)S(=O)(=O)C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	36.175
[H]N(C1=C([H])C([H])=C([H])N=C1[H])C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H]	5000
[H]C1=NC(OC2=C(C([H])=C([H])N=C2[H])C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	490
[H]C1=NC(OC2=C([H])C([H])=C(N=C2C([H])([H])[H])C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	5.4
[H]C1=NC(OC2=C([H])C(F)=C([H])N=C2[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	210
[H]C1=NC(OC2=C([H])C(C#N)=C([H])N=C2[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	260
[H]C1=NC(OC2=C([H])C([H])=C(OC([H])([H])[H])N=C2C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	132
[H]C1=NC(OC2=C([H])C([H])=C(N=C2C([H])([H])[H])S(=O)(=O)C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]	25
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]	131
[H]N(C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]	31
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])S2(=O)=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	1029
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	46
[H]N(C1=C([H])C2=C(OC([H])([H])C2=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	88
[H]N(C1=C([H])C2=C(OC([H])([H])C([H])([H])C2=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	272
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	734
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=N2)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]	117
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(OC([H])([H])[H])C([H])=N2)C([H])([H])C1([H])[H]	115
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=N2)C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	149
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	73
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NOC(=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	161
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NN=C(O2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	704
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NS2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	121
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=N2)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]	51
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	58
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	86
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C2([H])[H]	2610
[H]N(C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	177.5
[H]N(C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	270
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C2=C1S(=O)(=O)C([H])([H])C2([H])[H]	736
[H]N(C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	254
[H]N(C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	511
[H]N(C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)N([H])N2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	268
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	770
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	52
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)N([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	550
[H]C1=C([H])C(F)=C([H])C2=C1SC(=N2)C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(F)C1([H])[H]	18
[H]C1=C([H])C2=C(N=C(S2)C([H])([H])N2C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(F)C2([H])[H])C([H])=C1[H]	24
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(F)C1([H])[H])C(F)(F)F	4
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(S2)C([H])=C([H])C(F)=C3[H])C([H])([H])[C@]1([H])F	12
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[C@]1([H])F	485
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[C@]1([H])F	140
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[C@]1([H])OC([H])([H])[H]	100.5
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[C@]1([H])F	18
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(S2)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]	396
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(S2)C([H])=C([H])C(F)=C3[H])C([H])([H])C1([H])[H]	76
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])[H])C([H])([H])C1([H])[H]	441
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]	53
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]	1890
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]	1345
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]	74
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]	535
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])[H]	489
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C(F)=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F	131
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2F)S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F	122
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F	497
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CC1=NC=CC(COC2=CN=C(N=C2)N2CCN(CC2)C(=O)OC(C)(C)C)=C1	1937
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C[C@@H]1CN(CCN1C1=NC=C(OCC2CCN(CC2)S(C)(=O)=O)C=N1)C(=O)OC(C)(C)C	29
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C[C@H]1CN(C[C@@H](C)N1C1=NC=C(OCC2=CC=C(C=C2)S(C)(=O)=O)C=N1)C(=O)OC(C)(C)C	64
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C[C@@H]1CN(CCN1C1=NC=C(OCC2=NC=C(C=C2)S(C)(=O)=O)C=N1)C(=O)OC(C)(C)C	45
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]	2200
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CC1=NC=CC=C1OC1=C(F)C(=NC=N1)N1C2CC3CC1CC(C2)N3C(=O)OC1(C)CC1	8659
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CC1=NN(C=N1)C1=CC=C(OC2=C(C)C(=NC=N2)N2C3CC4CC2CC(C3)N4C(=O)OC(C)(C)C)C(F)=C1	403.5
CC1=NN(C=N1)C1=CC=C(OC2=C(C)C(=NC=N2)N2C3CC4CC2CC(C3)N4C(=O)OC(C)(C)C)C=C1	4729
CC1=C(OC2=CC=C(C=C2F)N2C=NC=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C	64.5
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CC1=C(OC2=CC=C(C=C2F)N2C=NN=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C	18
CC1=C(OC2=CC=C(C=C2F)N2C=NN=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC1(C)CC1	18.5
CC1=C(OC2=CC=C(C=C2)N2C=NC=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C	132.5
CC1=C(OC2=CC=C(C=C2)N2C=NN=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C	58
CC1=C(OC2=CC=C(C=C2)N2C=NN=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC1(C)CC1	43.5
CC(C)OC(=O)N1C2CC3CC1CC(C2)N3C1=NC=NC(OC2=CC=C(C=C2)N2C=CN=N2)=C1C	248
CS(=O)(=O)C1=CC=C([C@H]2CC[C@@H](CC2)OCC2CCN(CC3=NC(=NO3)C(F)(F)F)CC2)C(F)=C1	200
CC(C)(C)OC(=O)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CC=NC=C2F)CC1	63
CC(C)(C)OC(=O)N1CCC(COC2CCC(=CC2)C2=CC=NC=C2C#N)CC1	38
CC(C)(C)OC(=O)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CC=NC=C2C#N)CC1	1030
CC(C)(C)OC(=O)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CC=C(C=C2F)S(C)(=O)=O)CC1	13.7
CSC1=CC=C(C=C1)[C@H]1CC[C@@H](CC1)OCC1CCN(CC1)C(=O)OC(C)(C)C	505
CC(C)OC(=O)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CC=C(C=C2)S(C)(=O)=O)CC1	36.5
CC1=C(C=CC(=N1)S(C)(=O)=O)[C@H]1CC[C@@H](CC1)OCC1CCN(CC1)C1=NC=C(C=N1)C(F)(F)F	42
CC(C)(F)C1=NOC(=N1)N1CCC(COC2CCC(=CC2)C2=CC=C(C=C2)S(C)(=O)=O)CC1	15
CS(=O)(=O)C1=CN=C(C=C1)[C@H]1CC[C@@H](CC1)OCC1CCN(CC1)C1=NC=C(C=N1)C(F)(F)F	134
CC(C)C1=NOC(=N1)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CC=C(C=C2F)S(C)(=O)=O)CC1	38
CC(C)(C)OC(=O)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CN=C(C=N2)S(C)(=O)=O)CC1	707
CC(C)(C)OC(=O)N1[C@H]2CC[C@H]1CC(C2)OC1=NC=NC(NC2=C(F)C=C(C=C2)S(C)(=O)=O)=C1[N+]([O-])=O	1.45
CC(C)(C)OC(=O)N1[C@H]2CC[C@H]1CC(C2)OC1=NC=NC(NC2=CC=C(C=C2)S(C)(=O)=O)=C1[N+]([O-])=O	9.95
CC(C)(C)OC(=O)N1[C@H]2CC[C@H]1CC(CNC1=NC=NC(NC3=C(F)C=C(C=C3)S(C)(=O)=O)=C1[N+]([O-])=O)C2	6.7
CC(C)(C)OC(=O)N1[C@H]2CC[C@H]1CC(C2)NC1=NC=NC(NC2=C(F)C=C(C=C2)S(C)(=O)=O)=C1[N+]([O-])=O	1.5
CC(C)(C)OC(=O)N1[C@H]2CC[C@H]1CC(C2)NC1=NC=NC(NC2=CC=C(C=C2)S(C)(=O)=O)=C1[N+]([O-])=O	12