TargetNet
Q6V1X1
Dipeptidyl peptidase 8
Function
Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.
Database Links
| Database | Links |
|---|---|
| UniProt | Q6V1X1 |
| PDB | Not available |
| BioGrid | 120226 |
| BindingDB | Q6V1X1 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 2356 |
| PharmGKB | PA27470 |
| KEGG | hsa:54878 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 54878 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9065 | 0.005 |
| Accuracy | 0.8252 | 0.0076 |
| Sensitivity | 0.8465 | 0.0075 |
| Specificity | 0.8011 | 0.0106 |
| BEDROC | 0.9894 | 0.0036 |
| MCC Threshold | 0.476 | N/A |
| MCC | 0.6742 | N/A |
| F-score Threshold | 0.476 | N/A |
| F-score | 0.8493 | N/A |