Prostaglandin E2 receptor EP2 subtype
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Database | Links |
---|---|
UniProt | Q62053 |
PDB | Not available |
BioGrid | Not available |
BindingDB | Q62053 |
DrugBank | Not available |
Guide to PHARMACOLOGY | 341 |
PharmGKB | Not available |
KEGG | mmu:19217 |
BioCyc | Not available |
Entrez Gene (GeneID) | 19217 |
Metric | Mean Value | Standard Deviation |
---|---|---|
AUC | 0.944 | 0.0048 |
Accuracy | 0.8802 | 0.0068 |
Sensitivity | 0.8748 | 0.0103 |
Specificity | 0.8848 | 0.0073 |
BEDROC | 0.974 | 0.0151 |
MCC Threshold | 0.292 | N/A |
MCC | 0.8266 | N/A |
F-score Threshold | 0.292 | N/A |
F-score | 0.9073 | N/A |