TargetNet
Q16790
Carbonic anhydrase 9
Function
Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
Database Links
| Database | Links |
|---|---|
| UniProt | Q16790 |
| PDB | 2HKF, 3IAI |
| BioGrid | 107223 |
| BindingDB | Q16790 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA25998 |
| KEGG | hsa:768 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 768 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9854 | 4.5572 × 10-4 |
| Accuracy | 0.9532 | 0.0028 |
| Sensitivity | 0.9558 | 0.0032 |
| Specificity | 0.9499 | 0.0035 |
| BEDROC | 0.999 | 7.2383 × 10-4 |
| MCC Threshold | 0.478 | N/A |
| MCC | 0.9046 | N/A |
| F-score Threshold | 0.456 | N/A |
| F-score | 0.9578 | N/A |