TargetNet
Q16548
Bcl-2-related protein A1
Function
Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | Q16548 |
| PDB | 2VM6, 3I1H, 3MQP |
| BioGrid | 107069 |
| BindingDB | Q16548 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA25303 |
| KEGG | hsa:597 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 597 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.7951 | 0.011 |
| Accuracy | 0.73 | 0.0156 |
| Sensitivity | 0.7611 | 0.0287 |
| Specificity | 0.6944 | 0.0208 |
| BEDROC | 0.8286 | 0.0214 |
| MCC Threshold | 0.48 | N/A |
| MCC | 0.4665 | N/A |
| F-score Threshold | 0.474 | N/A |
| F-score | 0.7657 | N/A |