TargetNet
Q15761
Neuropeptide Y receptor type 5
Function
Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
Database Links
| Database | Links |
|---|---|
| UniProt | Q15761 |
| PDB | 2HE6 |
| BioGrid | 110949 |
| BindingDB | Q15761 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 308 |
| PharmGKB | PA31742 |
| KEGG | hsa:4889 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 4889 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.991 | 5.4724 × 10-4 |
| Accuracy | 0.9733 | 0.0013 |
| Sensitivity | 0.9673 | 0.0021 |
| Specificity | 0.979 | 0.002 |
| BEDROC | 0.9976 | 0.0013 |
| MCC Threshold | 0.47 | N/A |
| MCC | 0.9454 | N/A |
| F-score Threshold | 0.47 | N/A |
| F-score | 0.9718 | N/A |