TargetNet
Q15077
P2Y purinoceptor 6
Function
Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | Q15077 |
| PDB | 2B6R |
| BioGrid | 111070 |
| BindingDB | Q15077 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 326 |
| PharmGKB | PA32872 |
| KEGG | hsa:5031 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 5031 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.8966 | 0.0042 |
| Accuracy | 0.8331 | 0.01 |
| Sensitivity | 0.8374 | 0.0154 |
| Specificity | 0.8294 | 0.0158 |
| BEDROC | 0.9048 | 0.0115 |
| MCC Threshold | 0.376 | N/A |
| MCC | 0.6669 | N/A |
| F-score Threshold | 0.376 | N/A |
| F-score | 0.8273 | N/A |