TargetNet
Q02769
Squalene synthase
Function
Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway.
Database Links
| Database | Links |
|---|---|
| UniProt | Q02769 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | Q02769 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 645 |
| PharmGKB | Not available |
| KEGG | rno:29580 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 29580 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9701 | 0.0059 |
| Accuracy | 0.9166 | 0.0078 |
| Sensitivity | 0.9168 | 0.0109 |
| Specificity | 0.9164 | 0.0095 |
| BEDROC | 0.9995 | 3.906 × 10-4 |
| MCC Threshold | 0.516 | N/A |
| MCC | 0.8519 | N/A |
| F-score Threshold | 0.498 | N/A |
| F-score | 0.9273 | N/A |