TargetNet
Q01959
Sodium-dependent dopamine transporter
Function
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Database Links
| Database | Links |
|---|---|
| UniProt | Q01959 |
| PDB | Not available |
| BioGrid | 112422 |
| BindingDB | Q01959 |
| DrugBank | DB00182, DB00245, DB01156, DB01161, DB00907, DB01576, DB00937, DB00476, DB01463, DB00579, DB00422, DB00745, DB00830, DB00191, DB00721 |
| Guide to PHARMACOLOGY | 927 |
| PharmGKB | PA311 |
| KEGG | hsa:6531 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 6531 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9378 | 0.0015 |
| Accuracy | 0.8807 | 0.0036 |
| Sensitivity | 0.8991 | 0.0036 |
| Specificity | 0.8584 | 0.0056 |
| BEDROC | 0.9893 | 0.0037 |
| MCC Threshold | 0.54 | N/A |
| MCC | 0.7516 | N/A |
| F-score Threshold | 0.442 | N/A |
| F-score | 0.8877 | N/A |