TargetNet
Q01727
Melanocyte-stimulating hormone receptor
Function
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | Q01727 |
| PDB | Not available |
| BioGrid | 201338 |
| BindingDB | Q01727 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 282 |
| PharmGKB | Not available |
| KEGG | mmu:17199 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 17199 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9683 | 0.0038 |
| Accuracy | 0.914 | 0.0077 |
| Sensitivity | 0.9192 | 0.0142 |
| Specificity | 0.9092 | 0.0048 |
| BEDROC | 0.9827 | 0.0145 |
| MCC Threshold | 0.49 | N/A |
| MCC | 0.8544 | N/A |
| F-score Threshold | 0.49 | N/A |
| F-score | 0.9256 | N/A |