TargetNet
Q01726
Melanocyte-stimulating hormone receptor
Function
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | Q01726 |
| PDB | Not available |
| BioGrid | 110327 |
| BindingDB | Q01726 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 282 |
| PharmGKB | PA30673 |
| KEGG | hsa:4157 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 4157 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9709 | 0.0035 |
| Accuracy | 0.9209 | 0.0067 |
| Sensitivity | 0.9361 | 0.0092 |
| Specificity | 0.9078 | 0.0057 |
| BEDROC | 0.9806 | 0.0077 |
| MCC Threshold | 0.372 | N/A |
| MCC | 0.8272 | N/A |
| F-score Threshold | 0.372 | N/A |
| F-score | 0.9091 | N/A |