TargetNet
Q00788
Vasopressin V2 receptor
Function
Involved in renal water reabsorption (By similarity). Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | Q00788 |
| PDB | 2JX4 |
| BioGrid | Not available |
| BindingDB | Q00788 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 368 |
| PharmGKB | Not available |
| KEGG | rno:25108 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 25108 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.968 | 0.0019 |
| Accuracy | 0.928 | 0.0049 |
| Sensitivity | 0.9275 | 0.0072 |
| Specificity | 0.9284 | 0.0047 |
| BEDROC | 0.9711 | 0.0042 |
| MCC Threshold | 0.554 | N/A |
| MCC | 0.8713 | N/A |
| F-score Threshold | 0.48 | N/A |
| F-score | 0.9311 | N/A |