TargetNet
P81908
Cholinesterase
Function
Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | P81908 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P81908 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | Not available |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9471 | 0.0038 |
| Accuracy | 0.8926 | 0.005 |
| Sensitivity | 0.8954 | 0.0068 |
| Specificity | 0.8898 | 0.0061 |
| BEDROC | 0.9898 | 0.0035 |
| MCC Threshold | 0.46 | N/A |
| MCC | 0.7934 | N/A |
| F-score Threshold | 0.46 | N/A |
| F-score | 0.9011 | N/A |