TargetNet
P79208
Prostaglandin G/H synthase 2
Function
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Critical component of colonic mucosal wound repair (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | P79208 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P79208 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 443460 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.8281 | 0.0094 |
| Accuracy | 0.7536 | 0.01 |
| Sensitivity | 0.796 | 0.0137 |
| Specificity | 0.7036 | 0.0126 |
| BEDROC | 0.9253 | 0.01 |
| MCC Threshold | 0.506 | N/A |
| MCC | 0.5172 | N/A |
| F-score Threshold | 0.352 | N/A |
| F-score | 0.7915 | N/A |