TargetNet


P78396

Cyclin-A1


Function

May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.


Database Links

Database Links
UniProt P78396
PDB Not available
BioGrid 114417
BindingDB P78396
DrugBank Not available
Guide to PHARMACOLOGY Not available
PharmGKB PA26147
KEGG hsa:8900
BioCyc Not available
Entrez Gene (GeneID) 8900

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9446 0.0043
Accuracy 0.8914 0.0065
Sensitivity 0.8938 0.0121
Specificity 0.8886 0.0123
BEDROC 0.9983 0.002
MCC Threshold 0.564 N/A
MCC 0.7936 N/A
F-score Threshold 0.54 N/A
F-score 0.901 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:44