TargetNet


P70536

Oxytocin receptor


Function

Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system.


Database Links

Database Links
UniProt P70536
PDB Not available
BioGrid Not available
BindingDB P70536
DrugBank Not available
Guide to PHARMACOLOGY 369
PharmGKB Not available
KEGG rno:25342
BioCyc Not available
Entrez Gene (GeneID) 25342

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9761 0.0019
Accuracy 0.933 0.0032
Sensitivity 0.9184 0.0066
Specificity 0.9454 0.0036
BEDROC 0.9868 0.0061
MCC Threshold 0.504 N/A
MCC 0.868 N/A
F-score Threshold 0.504 N/A
F-score 0.9283 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:44