TargetNet
P61169
D(2) dopamine receptor
Function
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P61169 |
| PDB | Not available |
| BioGrid | 246498 |
| BindingDB | P61169 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 215 |
| PharmGKB | Not available |
| KEGG | rno:24318 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 24318 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9694 | 9.1603 × 10-4 |
| Accuracy | 0.9237 | 0.0018 |
| Sensitivity | 0.9498 | 0.0019 |
| Specificity | 0.8944 | 0.0024 |
| BEDROC | 0.9877 | 0.0013 |
| MCC Threshold | 0.502 | N/A |
| MCC | 0.8525 | N/A |
| F-score Threshold | 0.48 | N/A |
| F-score | 0.9318 | N/A |