TargetNet
P55263
Adenosine kinase
Function
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Database Links
| Database | Links |
|---|---|
| UniProt | P55263 |
| PDB | 1BX4, 2I6A, 2I6B |
| BioGrid | 106644 |
| BindingDB | P55263 |
| DrugBank | DB00640, DB00131, DB00171, DB00061, DB00811 |
| Guide to PHARMACOLOGY | 1231 |
| PharmGKB | PA24579 |
| KEGG | hsa:132 |
| BioCyc | MetaCyc:HS08097-MONOMER |
| Entrez Gene (GeneID) | 132 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9837 | 0.0013 |
| Accuracy | 0.9374 | 0.0056 |
| Sensitivity | 0.9547 | 0.0069 |
| Specificity | 0.9222 | 0.0057 |
| BEDROC | 0.9993 | 2.3295 × 10-4 |
| MCC Threshold | 0.464 | N/A |
| MCC | 0.8834 | N/A |
| F-score Threshold | 0.464 | N/A |
| F-score | 0.939 | N/A |