TargetNet
P55157
Microsomal triglyceride transfer protein large subunit
Function
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B.
Database Links
| Database | Links |
|---|---|
| UniProt | P55157 |
| PDB | Not available |
| BioGrid | 110641 |
| BindingDB | P55157 |
| DrugBank | DB01094 |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | PA164742099 |
| KEGG | hsa:4547 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 4547 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 1 | 1.1252 × 10-5 |
| Accuracy | 0.9979 | 0.0014 |
| Sensitivity | 1 | 0 |
| Specificity | 0.9961 | 0.0027 |
| BEDROC | 1 | 9.7943 × 10-8 |
| MCC Threshold | 0.514 | N/A |
| MCC | 1 | N/A |
| F-score Threshold | 0.514 | N/A |
| F-score | 1 | N/A |