TargetNet
P50052
Type-2 angiotensin II receptor
Function
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Database Links
| Database | Links |
|---|---|
| UniProt | P50052 |
| PDB | Not available |
| BioGrid | 106692 |
| BindingDB | P50052 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 35 |
| PharmGKB | PA44 |
| KEGG | hsa:186 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 186 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9771 | 0.0027 |
| Accuracy | 0.9409 | 0.0057 |
| Sensitivity | 0.9451 | 0.0077 |
| Specificity | 0.9359 | 0.0053 |
| BEDROC | 0.9914 | 0.0052 |
| MCC Threshold | 0.488 | N/A |
| MCC | 0.8879 | N/A |
| F-score Threshold | 0.488 | N/A |
| F-score | 0.9482 | N/A |