TargetNet
P48145
Neuropeptides B/W receptor type 1
Function
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Database Links
| Database | Links |
|---|---|
| UniProt | P48145 |
| PDB | Not available |
| BioGrid | 109092 |
| BindingDB | P48145 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 303 |
| PharmGKB | PA28912 |
| KEGG | hsa:2831 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 2831 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.8765 | 0.0087 |
| Accuracy | 0.8293 | 0.0068 |
| Sensitivity | 0.8517 | 0.014 |
| Specificity | 0.805 | 0.0099 |
| BEDROC | 0.9503 | 0.0183 |
| MCC Threshold | 0.382 | N/A |
| MCC | 0.6795 | N/A |
| F-score Threshold | 0.382 | N/A |
| F-score | 0.8536 | N/A |