TargetNet
P47936
Cannabinoid receptor 2
Function
Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
Database Links
| Database | Links |
|---|---|
| UniProt | P47936 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P47936 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 57 |
| PharmGKB | Not available |
| KEGG | mmu:12802 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 12802 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9834 | 0.001 |
| Accuracy | 0.9592 | 0.0034 |
| Sensitivity | 0.9593 | 0.0065 |
| Specificity | 0.9592 | 0.0037 |
| BEDROC | 0.9808 | 0.0077 |
| MCC Threshold | 0.446 | N/A |
| MCC | 0.9211 | N/A |
| F-score Threshold | 0.446 | N/A |
| F-score | 0.9596 | N/A |