TargetNet
P47901
Vasopressin V1b receptor
Function
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P47901 |
| PDB | Not available |
| BioGrid | 107034 |
| BindingDB | P47901 |
| DrugBank | DB00035, DB02638, DB00067 |
| Guide to PHARMACOLOGY | 367 |
| PharmGKB | PA25188 |
| KEGG | hsa:553 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 553 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9815 | 0.0042 |
| Accuracy | 0.9377 | 0.0073 |
| Sensitivity | 0.9535 | 0.0072 |
| Specificity | 0.9184 | 0.0094 |
| BEDROC | 0.9949 | 0.0051 |
| MCC Threshold | 0.416 | N/A |
| MCC | 0.8911 | N/A |
| F-score Threshold | 0.416 | N/A |
| F-score | 0.9517 | N/A |