TargetNet
P47898
5-hydroxytryptamine receptor 5A
Function
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.
Database Links
| Database | Links |
|---|---|
| UniProt | P47898 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P47898 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 10 |
| PharmGKB | PA29558 |
| KEGG | hsa:3361 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 3361 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.8869 | 0.004 |
| Accuracy | 0.8408 | 0.0126 |
| Sensitivity | 0.7993 | 0.0193 |
| Specificity | 0.8877 | 0.0173 |
| BEDROC | 0.9992 | 2.0625 × 10-4 |
| MCC Threshold | 0.442 | N/A |
| MCC | 0.7069 | N/A |
| F-score Threshold | 0.442 | N/A |
| F-score | 0.8613 | N/A |