TargetNet


P46663

B1 bradykinin receptor


Function

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.


Database Links

Database Links
UniProt P46663
PDB Not available
BioGrid 107092
BindingDB P46663
DrugBank Not available
Guide to PHARMACOLOGY 41
PharmGKB PA79
KEGG hsa:623
BioCyc Not available
Entrez Gene (GeneID) 623

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9899 9.8351 × 10-4
Accuracy 0.9617 0.0024
Sensitivity 0.9709 0.0045
Specificity 0.952 0.0011
BEDROC 0.9987 9.8379 × 10-4
MCC Threshold 0.5 N/A
MCC 0.9276 N/A
F-score Threshold 0.5 N/A
F-score 0.9648 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:40