TargetNet


P43166

Carbonic anhydrase 7


Function

Reversible hydration of carbon dioxide.


Database Links

Database Links
UniProt P43166
PDB 3MDZ, 3ML5
BioGrid Not available
BindingDB P43166
DrugBank Not available
Guide to PHARMACOLOGY Not available
PharmGKB PA25996
KEGG hsa:766
BioCyc Not available
Entrez Gene (GeneID) 766

Chemical Space of the Positive Compounds


Model Performance Metrics

Metric Mean Value Standard Deviation
AUC 0.9526 0.0028
Accuracy 0.8985 0.0056
Sensitivity 0.8812 0.0093
Specificity 0.9144 0.0047
BEDROC 0.9663 0.0079
MCC Threshold 0.434 N/A
MCC 0.818 N/A
F-score Threshold 0.434 N/A
F-score 0.9063 N/A

Downloads

R Model Object

Random Forest model object (.RData)

Download RData

Positive Set

SMILES string + affinity value (.tsv)

Download TSV


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Page generated on: 2014-04-29 14:39:39