TargetNet
P42892
Endothelin-converting enzyme 1
Function
Converts big endothelin-1 to endothelin-1.
Database Links
| Database | Links |
|---|---|
| UniProt | P42892 |
| PDB | 3DWB |
| BioGrid | 108218 |
| BindingDB | P42892 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 1615 |
| PharmGKB | PA27594 |
| KEGG | hsa:1889 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 1889 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.952 | 0.0034 |
| Accuracy | 0.8954 | 0.0065 |
| Sensitivity | 0.9064 | 0.0134 |
| Specificity | 0.8824 | 0.0115 |
| BEDROC | 0.9988 | 5.1986 × 10-4 |
| MCC Threshold | 0.474 | N/A |
| MCC | 0.8111 | N/A |
| F-score Threshold | 0.474 | N/A |
| F-score | 0.9142 | N/A |