smile	binding.affinity
[H]OC1=C2\C(=C(/[H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	5600
[H]OC1=C2\C(=C(/[H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	829
[H]OC1=C2\C(=C(/[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	8700
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])C3=C([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[H])[C@@]1(C2=C(OC([H])=C2C(=O)O[C@]1([H])C([H])([H])OC([H])([H])[H])C3=O)C([H])([H])[H]	193
[H]OC1=C2\C(=C(\[H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])C(=O)[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	3100
[H]OC1=C2\C(=C(/[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	2920
[H]OC1=C2\C(=C(/[H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	6500
[H]OC1=C2\C(=C(\[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1470
[H]OC1=C2\C(=C(\[H])N(N3C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1210
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1690
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(\C([H])=C2\C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@]3(C2=C(O[H])C(=O)C2=C3[C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]23[H])C([H])([H])[H])C([H])([H])C1([H])[H]	822
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])C([H])(N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	568
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	831
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])C(=O)C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	960
[H]OC1=C2\C(=C(\[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	2290
[H]OC1=C2\C(=C(\[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1350
[H]OC1=C2\C(=C(\[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	3570
[H]OC1=C2\C(=C(\[H])N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	3560
[H]OC1=C2\C(=C(\[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	2330
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1800
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	692
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	249
[H]OC1=C2\C(=C(\[H])N(C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])O[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1870
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	890
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	619
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1200
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])C([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	2450
[H]OC1=C2\C(=C(\[H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C#N)C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	1690
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	961
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]	820
[H]N1N=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2SC(=C([H])C2=N1)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]	310
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	215
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	49
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	4
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]	6
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	7
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2450
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4.6
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	46
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	80.5
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	9.8
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1265
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	170
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1.4
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.51
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	22
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2.1
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1.1
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.46
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.83
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4.65
[H]OC([H])([H])C([H])([H])OC(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.32
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.605
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.475
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.32
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C3([H])[H])C(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]	0.08
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C([H])=C([H])N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	695
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C([H])=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	7300
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C2=C(N=C1[H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	120
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C2=C(N=C([H])C([H])=C2[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	5950
[H]OC([H])([H])C([H])([H])OC(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1.5
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.38
[H]N1C(=O)N([H])C2=C1C([H])=C([H])C(=C2[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	195
[H]N1C(=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	130
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	145
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	88
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	230
[H]N1C([H])=C([H])C2=C1C(=C([H])C([H])=C2[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	380
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	575
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	170
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	9
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]	1.975
[H]O[C@@]12O[C@@]([H])(C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]	9.6
[H]O[C@@]1([H])C([H])([H])C(=O)[C@@]([H])(\C([H])=C(C([H])([H])[H])\C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@@]2([H])C([H])([H])[C@@](O[H])(C(=O)C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C(=O)O[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C(=O)N([H])C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C3([H])[H])[C@]1([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]2([H])OC([H])([H])[H])C([H])([H])C([H])=C([H])[H]	1.45
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]3([H])OC(=O)[C@@]4([H])N(C(=O)C(=O)[C@]5(O[H])C([H])([H])[C@@]([H])([C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]5([H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@]([H])(O[H])[C@@]3([H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]2([H])OC([H])([H])[H])C([H])=C1[H]	1.88
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(\[H])=C(/C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])([C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]4([H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@]([H])(O[H])[C@@]2([H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]	2.075
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2OC(=C([H])C(=O)C2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2759
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C2[H])C(=O)C([H])=C(O1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	6400
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C2[H])C(=O)C([H])=C(O1)N1C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])[H])C1([H])[H]	4800
[H]C1=C([H])C2=C(C([H])=C1[H])C1=NC(=C([H])C(=O)N1C([H])=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5300
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1S2)C1=C2OC(=C([H])C(=O)C2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1700
[H]C1=C2C3=C(O1)C(=O)C1=C([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@@]4(C(=O)C([H])([H])C([H])([H])[C@@]14[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])[C@]([H])(OC2=O)C([H])([H])OC([H])([H])[H]	40
[H]O[C@]1([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]2([H])N(C(=O)C(=O)[C@]3(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]1([H])OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2N=NN=C2[H])[C@]([H])(OC([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]	3.3
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@]([H])(C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]	1.6
[H]O[C@]1([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@@]([H])(OC(=O)[C@@]2([H])N(C(=O)C(=O)[C@]3(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]1([H])OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)N(OC([H])([H])[H])C([H])([H])[H])[C@]([H])(OC([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]	5.8
[H]O[C@]1([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]2([H])N(C(=O)C(=O)[C@]3(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]1([H])OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2N=NC([H])=N2)[C@]([H])(OC([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]	4.8
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(O1)C(=O)N([H])C([H])([H])[H]	680
[H]N(C1=NN([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=NC(=NC(=N1)N([H])C([H])([H])[H])C([H])([H])[H]	100
[H]N(C1=NN([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=NC(=NC(=N1)N([H])C([H])([H])C#N)C([H])([H])[H]	73
[H]N(C1=NN([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C#N)C([H])([H])[H]	82
[H]C#CC([H])([H])N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN([H])C([H])=C1[H]	150
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C(F)=C(F)C([H])=C12)N([H])C1=NN([H])C([H])=C1[H]	45
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C1[H]	9
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]	420
[H]OC1=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C([H])C(O[H])=C1[H]	5
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C1[H]	190
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]	11
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]	180
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C1[H]	290
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C2=C(C([H])=C([H])N2[H])C([H])=C1[H]	140
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C2=C(C([H])=NN2[H])C([H])=C1[H]	120
[H]N([H])C1=NC(=NC(=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=NN([H])C([H])=C1[H])C([H])([H])[H]	41
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]	580
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN(C([H])=C1[H])C([H])(F)F	770
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NOC([H])=C1[H]	260
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN([H])C2=C1C([H])=C([H])C([H])=C2[H]	250
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])N([H])N=C1[H]	190
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC([H])=NC(=N2)N([H])[H])=C1[H]	34
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC([H])=NC([H])=N2)=C1[H]	3000
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC([H])=NC(N([H])[H])=C2[H])=C1[H]	420
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])C([H])([H])C#N)C([H])([H])[H])=C1[H]	12.5
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])C([H])([H])[H])=C1[H]	410
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]	4700
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(N([H])[H])=C2[H])C([H])([H])[H])=C1[H]	87
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC([H])=C2[H])C([H])([H])[H])=C1[H]	600
[H]OC1=C([H])C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC(=NC([H])=N2)N([H])C([H])([H])C#N)=C([H])C([H])=C1[H]	398.5
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC([H])=NC(=N2)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]	2300
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC([H])=NC(=N2)N([H])C([H])([H])[H])=C1[H]	250
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)[C@@](OC2([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]	16.4
[H]OC([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H]	17.125
[H]OC([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	49.35
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H]	7.7
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	14.625
[H]OC(C1=C([H])C2=NC(=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2S1)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]	3
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2OC([H])([H])C([H])([H])C([H])([H])C2=N1	10
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C(=N1)C([H])([H])C([H])([H])OC2([H])[H]	25
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C(=N1)C([H])([H])OC2([H])[H]	6
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]	5.1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=O)OC(C2=N1)(C([H])([H])[H])C([H])([H])[H]	5.75
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C(=O)OC(C2=N1)(C([H])([H])[H])C([H])([H])[H]	10.3
[H]OC([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]	3
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C#N)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]	15.6
[H]N(C(=O)N([H])C1([H])C([H])([H])OC1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]	18.25
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])[H]	2.975
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]	22.8
[H]N(C1=C([H])C([H])=C([H])C(=O)N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]	6.675
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)[C@@](OC2([H])[H])(C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]	3.075
[H]OC([H])([H])C([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H]	6.35
[H]OC([H])([H])C([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	7.21
[H]OC([H])([H])C([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]	7.64
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)[C@@](OC2([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C#N	6.85
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)[C@](OC2([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	40.5
[H]N([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C([H])([H])C([H])([H])[H])C(=N2)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H]	0.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	0.7
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])C([H])=C1[H]	0.18
[H]OC([H])([H])[C@]1([H])N(C2=NC(=NC(=N2)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])[C@]([H])(C([H])([H])O[H])C([H])([H])C1([H])[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	5.4
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	8.8
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.56
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]	0.535
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.56
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.635
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.34
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.14
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]	0.485
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.9
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.495
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.25
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]	1.65
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H]	2.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	7.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]	1.1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H]	1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H]	1.1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H]	0.89
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]	0.9
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]	0.8
[H]OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])C([H])=C1[H]	0.26
[H]N1C([H])=NC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C2C([H])=C([H])N([H])C2=C1[H]	150
[H]N1C([H])=NC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]	8900
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(C([H])=C([H])N2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	290
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	450
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4500
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C([H])([H])C([H])([H])[H])C(=N2)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H]	0.3
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C([H])([H])C([H])([H])[H])C(=N2)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H]	0.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	2.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(N=C1[H])N([H])C([H])([H])[H]	0.9
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(N=C1[H])N(C([H])([H])[H])C([H])([H])[H]	1.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	6
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	0.6
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]	0.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]	1.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.9
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]	0.29
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.44
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	20
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	1.4
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	16
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	4.7
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	58
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	57
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	32
[H]N([H])C1=C([H])C([H])=C(C([H])=N1)C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	35
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	100
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	22
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	26.5
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	11
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2SC([H])=C([H])C2=N1	49
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	51.5
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]	2100
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]	310
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]	160
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]	1700
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]	720
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]	2050
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]	4000
[H]OC1=C([H])N=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N([H])C2=N1	620
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.6
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	3.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.45
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	0.9
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	0.7
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	0.7
[H]OC([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	0.34
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	0.68
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	1.25
[H]OC1=C([H])N=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]	970
[H]OC1=C([H])N=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]	160
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C2[H])C([H])([H])C1([H])[H]	51
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	662.5
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]	7200
[H]OC1=C([H])N=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]	590
[H]OC1=C([H])N=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)N=C2[H])C([H])([H])C1([H])[H]	570
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N([H])C2=N1	2016.5
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N=C([H])N2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	910
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N=C([H])N2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	140
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]	170
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]	152
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(Cl)=C([H])N=C2[H])C([H])([H])C1([H])[H]	200
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.11
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]	0.48
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F	0.23
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F)C1=C([H])C([H])=C([H])N=C1[H]	0.19
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.2
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	1.9
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@]3([H])OC([H])([H])[C@@]2([H])C3([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F)C1=C([H])C([H])=C([H])N=C1[H]	9.1
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@]3([H])OC([H])([H])[C@@]2([H])C3([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F	27.45
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@]3([H])OC([H])([H])[C@@]2([H])C3([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F	48.25
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]	84
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(N=C1[H])N([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	10
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H]	1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.6
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.215
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H]	18
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	500
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H]	3.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.16
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])C([H])([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]	1.335
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F)C1=C([H])C([H])=C([H])N=C1[H]	0.2
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F	0.56
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.17
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.22
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.62
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])C([H])([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.43
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.62
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])C([H])([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]	1.5
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	2.3
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.22
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H]	2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	1.8
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	5.2
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H]	2.4
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	1.5
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4.2
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	2.45
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2.5
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C([H])N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	4000
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H]	1.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	3.9
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	10
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	11.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]	3.9
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	6.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]	6.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	9.3
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]	1.9
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]	1.8
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	570
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]	750
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]	5900
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]	660
[H]N1C([H])=NC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])SC([H])=C1[H]	3900
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F	0.5
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.62
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	460
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=NC(=C([H])C([H])=C1[H])C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	550
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=NC(=C([H])S1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	560
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])SC(=N1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	180
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(O1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	52
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	23
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	550
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1500
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5500
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	510
[H]C1=C(OC(=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	520
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	21
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]	270
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NC2=C(N=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2500
[H]N1C([H])=NC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1	2800
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N=C([H])N2C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	600
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	90
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]	265
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(Br)C([H])=C2[H]	3700
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]	9200
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]	108
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]	153
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]	18
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H]	118
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C([H])N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C2=O)=C1[H]	1650
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	430
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C([H])N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H]	2125
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]	7
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]	11
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]	9
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])[C@@]7([H])O[C@]([H])(C([H])([H])C7([H])[H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	17
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6[C@@]7([H])C([H])([H])C([H])([H])[C@]6([H])C([H])([H])OC7([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	5.4
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])OC([H])([H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	18
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	115
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	10.5
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5[C@@]6([H])C([H])([H])C([H])([H])[C@]5([H])C([H])([H])OC6([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	42
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])OC([H])([H])[C@]5([H])C([H])([H])C6([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	7.5
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N([H])C([H])([H])C6=C([H])N=C([H])C([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	9
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	11
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	8.2
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])C([H])([H])C([H])([H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	27.85
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	70
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]	180
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	0.72
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	17
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	19
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	2.2
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]	0.38
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C([H])([H])[H]	2.1
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	2.75
[H]OC1=C([H])C2=C(C(=O)\C(O2)=C(/[H])C2=C([H])N(C3=C2C(=C([H])C([H])=N3)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(O[H])=C1[H]	0.94
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.4
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]	0.9
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]	500
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H]	5000
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1625
[H]N1C([H])=C([H])C2=C1C(=NC(=N2)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5000
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	355
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	430
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	108
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	3600
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N(C([H])=C2[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4000
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])(OC([H])([H])[H])OC([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])=O)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	52
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	11
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	24
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	14
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]	2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.6
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.4
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	1.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.5
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	111
[H]N([H])C1=C([H])C([H])=C([H])C(=N1)C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	113
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	125
[H]N([H])C1=C([H])N=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	145
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]	170
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	2.8
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	1.4
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]	62
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]	800
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=C([H])C([H])=C([H])N=C1[H]	1
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	10
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]	205
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]	190
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H]	123
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=N1	22
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]	3
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C(Br)C([H])=C2[H])C([H])([H])[H]	190
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	29
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.4
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	4.6
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N(C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4000
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5900
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2000
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	3650
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	205
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	64
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	800
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	800
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1	7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]	8
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	30
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	33
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	2.4
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	2.6
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	2.7
[H]N([H])C1=C([H])C([H])=C(C([H])=N1)C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	9.6
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	12
[H]N(OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	16
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	16
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	20
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.8
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.8
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	65
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	73
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	76
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	84
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	200
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	10
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	50
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	59
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	21
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	30
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	10
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	4
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C3C([H])=NN(C3=N2)C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]	0.1
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.2
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.3
[H]OC([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	0.3
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.5
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]	0.6
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.6
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])N1[H]	0.7
[H]N(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	23
[H]N(OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	23
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	27
[H]C1=NN(C2=NC(=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	480
[H]OC([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C2C(N=C(N=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=N1	51.5
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C(N=C(N=C1[H])N([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]	750
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C2C([H])=NN([H])C2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]	130
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C([H])N=C(N=C1[H])N([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]	30
[H]N([H])C1=NC(=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	880
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]	57
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]	9.5
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=NC([H])=C([H])C(=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]	3500
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(=C34)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C2=O)C([H])=C1[H]	37
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=NC([H])=C([H])C(=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]	3.475
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]	4.55
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]	18
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H]	18
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C([H])N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C2=O)=C1[H]	215
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)=C1[H]	96
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]	4
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])OC([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	71
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	29
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	14.3
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	145
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]	5.6
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C6=C([H])C([H])=C([H])N=C6[H])C([H])([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	13
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=C([H])C([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	102.5
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=C([H])C([H])=N6)C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	8.4
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=NC([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	9.3
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])N=C([H])C([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]	10.9
[H]OC1=C([H])C2=C(C(=O)\C(O2)=C(/[H])C2=C([H])N(C3=C2C(=C([H])C([H])=C3[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(O[H])=C1[H]	33
[H]OC1=C([H])C2=C(C(=O)\C(O2)=C(/[H])C2=C([H])N(C3=C2C([H])=C([H])C([H])=N3)C([H])([H])[H])C(O[H])=C1[H]	42
[H]OC1=C([H])C2=C(C(=O)\C(O2)=C(/[H])C2=C([H])N(C3=C2C(=C([H])C([H])=N3)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(O[H])=C1[H]	0.46
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]	19
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]	0.55
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	0.67
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	0.5
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	1.4
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]	0.56
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	2
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	1
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	3.1
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C1([H])[H])C([H])([H])[H]	0.39
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	1.85
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]	0.75
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]	2.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]	1.21
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	2.2
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]	250
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.85
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.63
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.51
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.84
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.89
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.57
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	2.95
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.57
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.19
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	0.26
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])[H]	1.34
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C([H])([H])[H]	0.43
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])S1	3.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1	3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1	3.05
[H]N(C(=O)N([H])C1=C([H])C([H])=NC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H]	21
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]	1.6
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C3N=NN(C3=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]	0.32
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C3N=NN(C3=N2)C([H])([H])C([H])([H])[H])C([H])=C1[H]	0.39
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C3N=NN(C3=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]	0.31
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]	2.55
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	0.35
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H]	0.56
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]	0.8
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C([H])([H])C([H])([H])[H])C(=N2)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H]	0.1
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C([H])([H])C([H])([H])[H])C(=N2)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H]	0.1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N=C1[H]	1
[H]OC([H])([H])C([H])([H])N1N=C([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	2.85
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	14.5
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H]	0.22
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2N=C([H])C3=C(N=C(N=C23)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C2[H])N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C1([H])[H]	0.27
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]	0.355
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])C(OC([H])([H])[H])(OC([H])([H])[H])C([H])([H])C1([H])[H]	0.74
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H]	0.21
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H]	1.19
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H]	0.26
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H]	0.22
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H]	0.22
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	0.16
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	0.12
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.12
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]	0.75
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	460
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.6
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	0.6
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	13
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	1.1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	51
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	0.1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1	1.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]	1.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]	1.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NN=C1[H]	2.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]	2.5
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]	1.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.4
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	1
COC1=C(OC)C=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1	93.5
O=C(NC1=CC=CC=C1)NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2	1.65
FC1=CC=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1	1.9
O=C(NC1=CC=C(C=C1)C#N)NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2	3.3
CC1=CC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N([C@H]2CC[C@H](O)CC2)C1=O	0.85
OCC1=CC=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1	0.43
OCCC1=CC=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1	0.32
CN(C)C1=CC=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1	13.5
CN1CCN(CC1)C1=CC=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1	1.1
CN(C)CCOC1=CC=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1	1.85
CN1CCN(CC2=CC=C(NC(=O)NC3=CC=C(C=C3)C3=NC(=NC(=N3)N3CCOCC3)N3C4CCC3COC4)C=C2)CC1	0.8
O=C(NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2)NC1=CN=CC=C1	0.5
O=C(NC1=CC=NC=C1)NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2	0.42
ClC1=NC=CC(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)=C1	1.26
O=C(NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2)NC1=CN=C(C=C1)C1=CN=CC=C1	3.45
O=C(NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2)NC1=CN=CN=C1	0.73
O=C(NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2)NC1=CN=NC=C1	1.55
O[C@H]1CC2COCC1N2C1=NC(=NC(=N1)C1=CC=C(NC(=O)NC2=CC=NC=C2)C=C1)N1CCOCC1	0.8
COC1=CC=C(C=C1)C1=CC2=C3N(C(=O)C=CC3=CN=C2C=C1)C1=CC=C(N2CCNCC2)C(=C1)C(F)(F)F	78.9
FC(F)(F)C1=CC(=CC=C1N1CCNCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CSC2=C1C=CC=C2	93.8
FC(F)(F)C1=CC(=CC=C1N1CCNCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CC=CC2=C1SC1=C(S2)C=CC=C1	3440
FC(F)(F)C1=CC(=CC=C1N1CCNCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=CC2=CC=CC=C12	23.35
COC1=NC=C(C(OC)=N1)C1=CC2=C3N(C(=O)C=CC3=CN=C2C=C1)C1=CC=C(N2CCNCC2)C(=C1)C(F)(F)F	662
FC(F)(F)C1=CC(=CC=C1N1CCNCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CC=C2C=CC=CC2=C1	213
COC1=NC=C(C=C1)C1=CC2=C(C)N=C(N)N=C2N(C(C)C)C1=O	5
COC1=NC=C(C=C1)C1=CC2=C(OC)N=C(N)N=C2N(C(C)C)C1=O	4000
[H]N([H])C1=NC2=C(N=C(C3=C([H])N([H])N=C3[H])C(=O)N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)C([H])([H])[H]	9
CC(C)N1C(=O)C(=NC2=C(C)N=C(N)N=C12)C1=CC=NN1	6
CC(C)N1C(=O)C(=NC2=C(C)N=C(N)N=C12)C1=CN=NN1	113
COC1=C(C=CC=N1)C1=NC2=C(C)N=C(N)N=C2N(C(C)C)C1=O	3940
COC1=NC=C(C=C1)C1=NC2=C(C)N=C(N)N=C2N(C(C)C)C1=O	30
COC1=NC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N(C(C)C)C1=O	18
COC1=NC=CC(=C1)C1=NC2=C(C)N=C(N)N=C2N(C(C)C)C1=O	947
CC1=CC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N([C@H]2CC[C@@H](CC2)OCCO)C1=O	5.11
CC1=C2N=C(C3=NNC=C3)C(=O)N(C3CCOCC3)C2=NC(N)=N1	0.8
COC1=CC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N([C@H]2CC[C@H](O)CC2)C1=O	6.8
CC1=CC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N(C2CCOCC2)C1=O	5
CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	1.3625
OC(=O)N1CCN(CC1)C1=CC=C(NC2=C3C=C(C=CC3=NC=C2)C2=CN=C3C=CC=CC3=C2)C=C1C(F)(F)F	1700
COCCC(=O)N1CCN(CC1)C1=CC=C(NC2=C3C=C(C=CC3=NC=C2)C2=CN=C3C=CC=CC3=C2)C=C1C(F)(F)F	966
CN(C)CCC(=O)N1CCN(CC1)C1=CC=C(NC2=C3C=C(C=CC3=NC=C2)C2=CN=C3C=CC=CC3=C2)C=C1C(F)(F)F	3810
FC(F)(F)C1=CC(=CC=C1N1CCNCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CC=C2OCCOC2=C1	66.5
FC(F)(F)C1=CC(=CC=C1N1CCNCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CC=C2OCOC2=C1	82.6
CS(=O)(=O)NC1=CC=C(C=C1)C1=CC2=C3N(C(=O)C=CC3=CN=C2C=C1)C1=CC=C(N2CCNCC2)C(=C1)C(F)(F)F	45.9
FC(F)(F)C1=CC(=CC=C1N1CCNCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CSC=C1	214
FC(F)(F)C1=CC(=CC=C1N1CCOCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	25.8
O=C1C=CC2=CN=C3C=CC(=CC3=C2N1C1=CC=C(C=C1)S(=O)(=O)N1CCNCC1)C1=CN=C2C=CC=CC2=C1	239
COC1=CC(=CC=C1N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1)N1CCC(N)CC1	95
CN1CCN(CC2=CC=C(C=C2)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C23)C2=CN=C3C=CC=CC3=C2)CC1	66
FC(F)(F)C1=CC(=CC=C1N1CCN(CC1)C(=O)C1CC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	6.84
CN(C)CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	3.6
CN1CCN(CC(=O)N2CCN(CC2)C2=CC=C(C=C2C(F)(F)F)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C23)C2=CN=C3C=CC=CC3=C2)CC1	0.57
CN(C)CCN1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	389
CN1CCN(CC1)C(=O)C1=CC=C(C=C1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	1.26
CCC(=O)N1CCC(=CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	21.4
FC(F)(F)C1=CC(=CC=C1C1CCN(CC1)C(=O)CN1CCOCC1)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	4.25
CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)C(C)=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	26.6
CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)C=C(C)C2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	51.9
CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)N(C)C(=O)C2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	230
CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)NCC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	396
CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)N(C)CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	287
CCC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)OCC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	336
CC(=O)N1CCN(CC1)C1=CC=C(C=C1C(F)(F)F)N1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1	5.4
[H]N([H])C1=C([H])C([H])=C(C#CC2=NN([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]	7885
[H]N1N=C(C#CC2=C([H])C([H])=C([H])N=C2[H])C2=C([H])C([H])=C([H])N=C12	7500
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]	265
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])C([H])=NN3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]	984
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1[H])C([H])([H])[H]	3
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1[H])C([H])([H])[H]	13
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1[H])C([H])([H])[H]	1330
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]	31
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])N=C(C([H])=C3[H])C([H])([H])[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]	3250
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]	66
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]	1000
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]	162
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N=C2N([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]	5
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])N=C4N([H])C([H])=C([H])C4=C3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]	216
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C2N([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]	17
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N([H])N=C1[H])C([H])([H])[H]	21
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N([H])N=C1[H])C([H])([H])[H]	84
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]	4000
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])N=C(OC([H])([H])[H])C([H])=C3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]	1000
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C2C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H]	1600
[H]OC([H])([H])C(C(=O)O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H])(C([H])([H])[H])C([H])([H])O[H]	1950
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C(N([H])C(=O)N([H])C3=C([H])C([H])=C(Cl)C(=C3[H])C(F)(F)F)=C([H])C([H])=C2C([H])([H])[H])C([H])=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	3018
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N2C(=NC([H])=C2C2=NOC(=N2)C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]	39
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC2=C([H])C([H])=C([H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2F)=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C(F)=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(F)C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=N1	3010
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])=N1	913
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=N1	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	57
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	285
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	262
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F	45
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F	6000
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]	47
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	719
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]	65
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]	269
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]	29
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]	11
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C([H])C(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	15
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]	1500
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(C#N)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]	1.6
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H]	6
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]	2.1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C1[H]	1.6
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]	2.1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]	2.1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2F)=C1[H]	1.1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(F)=C2[H])=C1[H]	2.3
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	2
[H]C1=C([H])C2=C(SC3=C(S2)C([H])=C([H])C([H])=C3C2=C([H])C(=O)C([H])=C(O2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]	9300
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2OC3=C(C([H])=C([H])C([H])=N3)C2=N1	12
[H]OC1=C([H])C2=C(N([H])C(=C2[H])C2=NN(C3=C2C(=NC([H])=N3)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]	5.5
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NC2=NC(=NC(N3C([H])([H])C([H])([H])OC([H])([H])[C@]3([H])C([H])([H])[H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])[H]	0.465
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	24
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])SC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	33
[H]N(C(=O)C([H])([H])[H])C1=C([H])N2N=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	0.4
[H]N([H])C1=C([H])N2N=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	35
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=NN2C([H])=C([H])N=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	49
[H]N(C(=O)C([H])([H])[H])C1=C([H])N2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	6.6
[H]N([H])C1=C([H])N2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	20
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])N2C([H])=C([H])N=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	229
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(N1[H])C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	20
[H]N([H])C1=NC2=C(N1[H])C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	430
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C2=C(N=C([H])N2[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	446
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	146
[H]N([H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]	70
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C2=C(N=C([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	76
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C2=C(SN=C2[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	292
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C(C([H])=C1[H])N1C(=O)C([H])=C([H])C2=C1C1=C([H])C(=C([H])C([H])=C1N=C2[H])C1=C([H])C2=C(N=C1[H])C([H])=C([H])C([H])=C2[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	3.01
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	8.2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	7.7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	5.6
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])[H]	14.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	22.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]	18.5
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC2([H])C([H])([H])OC2([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])(C([H])([H])[H])C([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])(C([H])([H])[H])C([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])(C([H])([H])[H])C([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	0.4
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]	1.1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	0.4
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	0.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1.7
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(O[C@@]3([H])C([H])([H])[C@@]4([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C4([H])[H])C3([H])[H])=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]	5.3
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=O)N=C(N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1200
[H]N(C(=O)C1=C([H])C([H])=C2C3=C(C([H])=C(S3)C(=O)N(C3=C([H])C([H])=C(C([H])=C3Cl)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC2=C1[H])C([H])([H])[H]	530
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]	1270
[H]N1N=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	150
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]	2440
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	630
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C(O[H])=C1[H]	1050
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]	1930
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	780
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C([H])([H])OC([H])([H])[H]	2380
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]	1020
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	340
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	2880
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1670
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1([H])[H]	5000
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	60
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	130
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	8300
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	70
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]	120
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]	8900
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]	322
[H]N1N=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	9
[H]N1C([H])=C([H])N=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	9
[H]N1C([H])=C([H])N=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	55
[H]N1C([H])=NC([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	2020
[H]N1C(=O)N(C2=NC(=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	580
[H]N1C(=O)N(C2=NC(=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	1360
[H]N1N=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	1690
[H]N1N=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	120
[H]N1C(=O)N(C2=NC(=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	170
[H]N1N=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	411.5
[H]N1C([H])=NC2=C1N=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	390
[H]N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	30
[H]N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	137
[H]N([H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	10
[H]N([H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	92
[H]N(C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	2503
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	50
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	63
[H]N1C([H])=C([H])C2=C1C([H])=C(C([H])=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	3500
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])(F)F)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	350
[H]N(C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1N=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]	570
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H]	95
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H]	420
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])C([H])([H])[H]	61
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1N=C(C([H])=C1C([H])([H])C([H])([H])[H])C(F)(F)F	280.5
[H]N1C([H])=C([H])C2=C1C(=C([H])C([H])=C2C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H])C([H])([H])[H]	51
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H]	1040
[H]N1N=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	1590
[H]N1C(=O)C2=C(C3=C([H])C([H])=C(Cl)C(Cl)=C3N2C([H])([H])[H])[C@@]([H])(C#N)[C@@]11C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]	9100
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N=C1C1=C([H])C([H])=C([H])C(O[H])=C1[H])C(=NC(=N2)N([H])[H])N([H])[H]	620
[H]OC([H])([H])C([H])([H])N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H]	234
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(C3=C([H])C([H])=NC([H])=C3[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	0.41
[H]N(C1=NC2=C([H])C(=C([H])C([H])=C2N=C1[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5.3
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C2=C(C([H])=C([H])N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	3.9
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	5
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=NC([H])=C4[H])C([H])([H])C3([H])[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	3.9
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	37
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(C3=C([H])N=C([H])C([H])=C3[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]	1.6
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	3900
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])OC([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	500
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])O[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	3900
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])N([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	1100
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	2100
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N(C([H])=O)[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	2800
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	2600
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]	3900
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]	300
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@]([H])(C4=C([H])N([H])C5=C4C([H])=C([H])C([H])=C5C([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@@]([H])(C([H])([H])[H])[C@@]([H])(O[H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]	10
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@]([H])(C4=C5N([H])C([H])=C(C5=C([H])C([H])=C4[H])C([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]	5
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C([H])([H])C([H])([H])S(=O)(=O)C2([H])[H]	28.5
[H]N([H])C(=O)[C@@]1([H])N(C(=O)N([H])C2=NC(=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]	9100
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H])C1=NC(=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])[H]	9100
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])[H]	9100
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=NN(N=N1)C([H])([H])C([H])([H])[H])C1=NC(=C(S1)C1=C([H])C([H])=C(C(F)=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]	9100
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])N2C([H])=C(N=C2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H]	2290
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])N2C([H])=C(N=C2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	751
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])N2C([H])=C(N=C2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5000
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])N3C([H])=C(N=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C3=N2)C2=C([H])N=C(N=C2[H])N([H])[H])C([H])([H])C1([H])[H]	989
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])N2C([H])=C(N=C2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]	5000
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])N2C([H])=C(N=C2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	5000
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])N2C([H])=C(N=C2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]	5000
[H]N([H])C(=O)C1=C([H])N2C([H])=C(N=C(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2=N1)C1=C([H])N=C(N=C1[H])N([H])[H]	237
[H]N([H])C1=NC(=C2C([H])=C(C(=O)N(N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=N1)C1=C([H])C(F)=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]	272
[H]N([H])C1=NC(=C2C([H])=C(C3=C([H])N([H])N=C3[H])C(=O)N(N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=N1)C([H])([H])[H]	10.6
[H]N([H])C1=NC(=C2C([H])=C(C3=C([H])N([H])N=C3[H])C(=O)N(N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=N1)C([H])([H])[H]	123
[H]N([H])C1=NC(=C2C([H])=C(C3=C([H])N([H])N=C3[H])C(=O)N(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=N1)C([H])([H])[H]	663
[H]N([H])C1=NC(=C2C([H])=C(C3=C([H])N([H])N=C3[H])C(=O)N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]	23.5
[H]N([H])C1=NC(=C2C([H])=C(C3=C([H])N([H])N=C3[H])C(=O)N(C2=N1)C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]	190
[H]N([H])C1=NC(=C2C([H])=C(C3=C([H])N([H])N=C3[H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]	51.2
[H]N([H])C1=NC(=C2C([H])=C(C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]	76.4
[H]N([H])C1=NC(=C2C([H])=C(C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]	142
[H]N([H])C1=NC(=C2C([H])=C(C3=C([H])N([H])N=C3[H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]	18.6
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C(=N1)C([H])([H])S(=O)(=O)C2([H])[H]	45.5
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C(=N1)C([H])([H])S(=O)(=O)C2([H])[H]	25
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C(=N1)C([H])([H])C([H])([H])S(=O)(=O)C2([H])[H]	50
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C([H])([H])C([H])([H])C([H])([H])S2(=O)=O	50
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])C([H])([H])[H])=C2C(=N1)C([H])([H])C([H])([H])S2(=O)=O	120
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C(=N1)C([H])([H])C([H])([H])S(=O)(=O)C2([H])[H]	30
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])OC([H])([H])[C@]2([H])C3([H])[H])=C2C(=N1)C([H])([H])S(=O)(=O)C2([H])[H]	676
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])C([H])([H])[H])=C2C(=N1)C([H])([H])S(=O)(=O)C2([H])[H]	14
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]	890
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]	4000
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]	4000
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]	88
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]	50
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]	45
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]	25
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N([H])C([H])([H])[H]	18
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C2[H])=C1[H]	18
[H]N([H])S(=O)(=O)C1=C(C([H])=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H]	16
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])[H]	15
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]	12
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])[H]	7.7
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]	4600
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]	3300
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])=C([H])C([H])=C1[H]	3200
[H]N([H])C1=NC([H])=C(N=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1F	623
[H]N([H])C1=NC([H])=C(N=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1C([H])([H])[H]	1781
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F	1700
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]	800
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C([H])=C1[H]	610
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])[H]	320
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C([H])C([H])=C1[H]	200
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]	140
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]	110
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])S(=O)(=O)C([H])([H])[H]	3600
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]	7400
[H]N([H])C1=NC(=NC(=N1)C1=C(N=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]	1400
[H]N([H])C1=NC(=NC(=N1)C1=C(N=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]	3700
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1400
[H]OC([H])([H])C1=C([H])N=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C2[H])C(=C1[H])C1=NC(=NC(=N1)N([H])[H])C([H])([H])[H]	2500
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]	5100
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]	290
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H]	560
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]	530
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C([H])=C2C2=NC(=NC(N([H])[H])=C2[H])C([H])([H])[H])=C1[H]	360
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]	7800
[H]N([H])C1=NC(=NC(=N1)C1=C([H])C([H])=C([H])N=C1N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])[H]	7200
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C([H])=C2C2=NC(=NC(=N2)C([H])([H])[H])N([H])[H])=C1[H]	200
[H]OC1=C([H])C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(=N2)C([H])([H])[H])=C([H])C([H])=C1[H]	7
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]	28
[H]N(C(=O)C1=C([H])C([H])=NO1)C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	37
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]	2600
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]	252
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H]	344
[H]N1C([H])=C([H])C2=C([H])C(=C([H])N=C12)C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	262
[H]N1C([H])=NC2=C([H])C(=C([H])C([H])=C12)C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	285
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	601
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1460
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	288
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1	3160
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1540
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	1380
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	5000
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]	1410
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])[C@@]2([H])OC([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	21
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC3=C2C([H])([H])C([H])([H])OC3(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	13
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C2(OC([H])([H])[H])C([H])([H])OC2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	9
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	10
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C(=NO1)C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	3
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C1([H])[H])N([H])C1=NN([H])C([H])=C1[H]	2
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])N=C([H])N1C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	5
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C1[H])N([H])C1=NN([H])C([H])=C1[H]	10
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])N=C([H])N=C1C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	3
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])N=C([H])N=C1[H])N([H])C1=NN([H])C([H])=C1[H]	2
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=NC(=C1[H])C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	4
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C([H])N=C1OC([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	39
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C(C([H])=C([H])N=C1[H])C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	2
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	21
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C([H])N=C1C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]	3
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C([H])N=C1[H])N([H])C1=NN([H])C([H])=C1[H]	3
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=NC([H])=C1[H])N([H])C1=NN([H])C([H])=C1[H]	6
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C(F)=C([H])C([H])=C1[H])N([H])C1=NN([H])C([H])=C1[H]	27
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C(F)C([H])=C([H])C([H])=C1[H])N([H])C1=NN([H])C([H])=C1[H]	15
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)N([H])C1=NN([H])C([H])=C1[H]	12
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])N=C([H])O1)N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]	20
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])N(N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]	16
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C(N=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]	15
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]	67
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)N([H])C1=NN([H])C([H])=C1[H]	9
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=NN12)N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]	55
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=NN=C([H])C(OC([H])([H])[H])=C2[H])=C1[H])C([H])([H])[H]	3
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=C([H])N(N=C2[H])[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]	36
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=NN=C(C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]	35
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=NN=C([H])C([H])=C2[H])=C1[H])C([H])([H])[H]	24
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=C([H])N=C([H])C([H])=C2[H])=C1[H])C([H])([H])[H]	147
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=C([H])N=C([H])C([H])=N2)=C1[H])C([H])([H])[H]	6
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=NN12)N([H])C1=NN([H])C([H])=C1[H]	3
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC([H])=C1[H])C([H])([H])[H]	141
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C([H])([H])[H])=C1[H])C([H])([H])[H]	63
[H]N([H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)N([H])C1=NN([H])C([H])=C1[H]	65
[H]N([H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=NN12)N([H])C1=NN([H])C([H])=C1[H]	13
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])N=C([H])N=C1[H])N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]	76
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H]	6300
[H]OC([H])([H])C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C(=O)C(=C([H])C3=C(N=C(N=C23)N([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C2[H])C([H])([H])C1([H])[H]	16
[H]N1N=C(N=C1[H])C1=C(C(C#N)=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]	434
[H]N1N=C([H])N=C1C1=C(C(C#N)=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]	2470
[H]N1N=C([H])N=C1C1=C(C(C#N)=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(F)C([H])=C(C#N)C([H])=C1[H]	1440
[H]N([H])C1=NC([H])=C(C2=NC(=NC(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F	4600
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	12
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	6.3
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]	14
[H]O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C3=C(S2)C(=NC(=N3)C2=C([H])N=C(N=C2[H])N([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]	17
[H]OC(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C3=C(S2)C(=NC(=N3)C2=C([H])N=C(N=C2[H])N([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]	14
CS(=O)(=O)N1CCN(CC2=CN3C=C(N=C(N4CCOCC4)C3=N2)C2=CN=C(N)N=C2)CC1	4880
CS(=O)(=O)N1CCN(CC2=C(Br)N3C=C(N=C(N4CCOCC4)C3=N2)C2=CN=C(N)N=C2)CC1	5100
CC1=C(CN2CCN(CC2)S(C)(=O)=O)N=C2N1C=C(N=C2N1CCOCC1)C1=CN=C(N)N=C1	1260
CS(=O)(=O)N1CCN(CC2=CN3C(=N2)C(=NC(=C3Cl)C2=CN=C(N)N=C2)N2CCOCC2)CC1	5710
[H][C@@]12CC[C@@]([H])(N1C(C)(C)C(=O)NC)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1	1.2
[H][C@@]12CC[C@@]([H])(N1C(=O)COC)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1	2.1
[H][C@@]12CC[C@@]([H])(N1C(C)=O)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1	1.2
[H][C@@]12CC[C@@]([H])(N1S(C)(=O)=O)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1	0.99
[H][C@@]12CC[C@@]([H])(N1C1COC1)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1	1.5
[H][C@]12CC[C@]([H])(N1C)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1	3.85
[H][C@@]12CC[C@@]([H])(N1C(C)=O)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C	7.5
[H][C@@]12CC[C@@]([H])(N1S(C)(=O)=O)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C	2.6
[H][C@]12CC[C@]([H])(N1C1COC1)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C	17.5
[H][C@@]12CC[C@@]([H])(N1CC)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C	6.5
[H][C@]12CC[C@]([H])(N1C)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C	4.2
CCNC(=O)NC1=CC=C(C=C1)C1=NC(N2CCOC[C@@H]2C)=C2CN(CCC2=N1)C1COC1	18
CC(C)(O)C1=NC=C(C=C1)C1=CN=C2NC(=O)CN(CC3CCOCC3)C2=N1	106
CC(C)(O)C1=NC=C(C=C1)C1=CN=C2NC(=O)N(CC3CCOCC3)C2=N1	176
O=C1CN(CCC2CCOCC2)C2=NC(=CN=C2N1)C1=CC=C(C=C1)C1=NNC=N1	8
O=C1NC2=NC=C(N=C2N1CCC1CCOCC1)C1=CC=C(C=C1)C1=NNC=N1	2
CNC(=O)C1=CC=CC(=C1)C1=CC=C2C(N=C(N=C2N2CCOC[C@@H]2C)N2CCOC[C@@H]2C)=N1	2.8
OP(O)(=O)O[C@H]1[C@@H](OCC2=CC=CC=C2)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O	1300
C[C@@H]1COCCN1C1=NC(=NC(=C1)C1(CC1)S(C)(=O)=O)C1=CC=CC2=C1C=CN2	1219
CS(=O)(=O)C1(CCNCC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1	865
CS(=O)(=O)C1(CCOCC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1	3300
CS(=O)(=O)C1(CC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1	1690
CC(C)(C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1)S(C)(=O)=O	1445
O=C1C=C(OC2=C1SC=C2C1=CC=C2OCCOC2=C1)N1CCOCC1	289
O=C1C=C(OC2=C1SC=C2C1=CC=CC=C1)N1CCOCC1	610
C[C@H](O)C(=O)N1CCC(CC1)N1C(=O)N(C)C2=C1C1=NC(=CC=C1N=C2)C1=C2C=NNC2=CC=C1	2.6
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=CN=C2NN=CC2=C1	0.243
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=C2C=NNC2=CC=C1	1.6
COCC(=O)N1CCC(CC1)N1C(=O)N(C)C2=C1C1=NC(=CC=C1N=C2)C1=CC=C(C)N=C1	0.377
CN1C(=O)N(C2CCN(CC2)C(=O)C(C)(C)O)C2=C1C=NC1=CC=C(N=C21)C1=CC=C(C)N=C1	10.2
CN1C(=O)N(C2CCN(CC2)C(=O)CO)C2=C1C=NC1=CC=C(N=C21)C1=CC=C(C)N=C1	0.842
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=CC=C(C)N=C1	2.3
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N(C4CCN(CC4)C(C)=O)C(=O)N3C)C2=N1	2.2
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N(C4CCN(C)CC4)C(=O)N3C)C2=N1	47
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N([C@H]4CC[C@H](O)CC4)C(=O)N3C)C2=N1	2
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N([C@H]4CC[C@@H](CC4)OCCO)C(=O)N3C)C2=N1	4.7
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N(C(=O)N3C)C3=CC=C(C=C3)C(C)(C)C#N)C2=N1	4.5
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2COC2)C(=N1)N1CCOC[C@@H]1C	3.8
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)S(C)(=O)=O)C(=N1)N1CCOC[C@@H]1C	4.2
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2CCCC2)C(=N1)N1CCOC[C@@H]1C	4.8
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C(C)C)C(=N1)N1CCOC[C@@H]1C	9.6
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=CN2C)C(=N1)N1CCOC[C@@H]1C	1.4
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=NC(C)=C2)C(=N1)N1CCOC[C@@H]1C	2.55
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=C(F)C=N2)C(=N1)N1CCOC[C@@H]1C	3.2
C[C@H]1COCCN1C1=NC(=NC2=C1CCN(C2)C1=NC=CC=N1)C1=CC=C(NC2=NC=CC(=O)N2)C=C1	0.4
O=C1NC(NC2=CC=C(C=C2)C2=NC3=C(CCN(C3)C3=NC=CC=N3)C(=N2)N2CCOCC2)=CC=C1	6.6
CCNC1=C(NC2=CC=C(C=C2)C2=NC3=C(CCN(C3)C3=NC=CC=N3)C(=N2)N2CCOC[C@@H]2C)C(=O)C1=O	13
C[C@H]1COCCN1C1=NC(=NC2=C1CCN(C2)C1=NC=CC=N1)C1=CC=C(NC2=NN(C)C(=O)N2)C=C1	2.9
C1CN(CCO1)C1=NC(=NC2=C1CCN(C2)C1=NC=CC=N1)C1=CC=C(NC2=NC=CC=N2)C=C1	220
FCCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=CC=N2)C(=N1)N1CCOCC1	2.7