TargetNet
P41968
Melanocortin receptor 3
Function
Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P41968 |
| PDB | Not available |
| BioGrid | 110329 |
| BindingDB | P41968 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 284 |
| PharmGKB | PA30675 |
| KEGG | hsa:4159 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 4159 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9571 | 0.0025 |
| Accuracy | 0.908 | 0.0041 |
| Sensitivity | 0.9162 | 0.0074 |
| Specificity | 0.9002 | 0.0058 |
| BEDROC | 0.9596 | 0.0125 |
| MCC Threshold | 0.472 | N/A |
| MCC | 0.8395 | N/A |
| F-score Threshold | 0.472 | N/A |
| F-score | 0.9188 | N/A |