TargetNet
P41149
Melanocortin receptor 5
Function
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
Database Links
| Database | Links |
|---|---|
| UniProt | P41149 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P41149 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 286 |
| PharmGKB | Not available |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | Not available |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9659 | 0.0043 |
| Accuracy | 0.9047 | 0.0092 |
| Sensitivity | 0.9074 | 0.0082 |
| Specificity | 0.9022 | 0.0119 |
| BEDROC | 0.9959 | 0.0027 |
| MCC Threshold | 0.394 | N/A |
| MCC | 0.8376 | N/A |
| F-score Threshold | 0.394 | N/A |
| F-score | 0.9167 | N/A |