TargetNet
P40238
Thrombopoietin receptor
Function
Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Database Links
| Database | Links |
|---|---|
| UniProt | P40238 |
| PDB | Not available |
| BioGrid | 110492 |
| BindingDB | P40238 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 1722 |
| PharmGKB | PA30923 |
| KEGG | hsa:4352 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 4352 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9561 | 0.0024 |
| Accuracy | 0.9196 | 0.0063 |
| Sensitivity | 0.9614 | 0.0112 |
| Specificity | 0.8842 | 0.0044 |
| BEDROC | 0.9481 | 0.013 |
| MCC Threshold | 0.464 | N/A |
| MCC | 0.8565 | N/A |
| F-score Threshold | 0.464 | N/A |
| F-score | 0.9234 | N/A |