TargetNet
P37288
Vasopressin V1a receptor
Function
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
Database Links
| Database | Links |
|---|---|
| UniProt | P37288 |
| PDB | 1YTV |
| BioGrid | 107033 |
| BindingDB | P37288 |
| DrugBank | DB00872, DB00035, DB00093, DB02638, DB00067 |
| Guide to PHARMACOLOGY | 366 |
| PharmGKB | PA25187 |
| KEGG | hsa:552 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 552 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9707 | 0.0012 |
| Accuracy | 0.9293 | 0.0022 |
| Sensitivity | 0.9155 | 0.0046 |
| Specificity | 0.9421 | 0.0042 |
| BEDROC | 0.9921 | 0.0042 |
| MCC Threshold | 0.47 | N/A |
| MCC | 0.8721 | N/A |
| F-score Threshold | 0.47 | N/A |
| F-score | 0.9329 | N/A |