TargetNet
P37268
Squalene synthase
Function
Not available.
Database Links
| Database | Links |
|---|---|
| UniProt | P37268 |
| PDB | 1EZF, 3ASX, 3LEE, 3Q2Z, 3Q30, 3V66, 3VJ8, 3VJ9, 3VJA, 3VJB, 3VJC |
| BioGrid | 108516 |
| BindingDB | P37268 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 645 |
| PharmGKB | PA28073 |
| KEGG | hsa:2222 |
| BioCyc | MetaCyc:HS01329-MONOMER |
| Entrez Gene (GeneID) | 2222 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9689 | 0.0037 |
| Accuracy | 0.8962 | 0.0109 |
| Sensitivity | 0.8906 | 0.0185 |
| Specificity | 0.9018 | 0.0056 |
| BEDROC | 0.9998 | 3.0002 × 10-5 |
| MCC Threshold | 0.414 | N/A |
| MCC | 0.8193 | N/A |
| F-score Threshold | 0.414 | N/A |
| F-score | 0.9117 | N/A |