TargetNet
P37136
Acetylcholinesterase
Function
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Database Links
| Database | Links |
|---|---|
| UniProt | P37136 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P37136 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | rno:83817 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 83817 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9433 | 0.0034 |
| Accuracy | 0.896 | 0.0068 |
| Sensitivity | 0.8949 | 0.0098 |
| Specificity | 0.8971 | 0.0097 |
| BEDROC | 0.9919 | 0.0041 |
| MCC Threshold | 0.426 | N/A |
| MCC | 0.7928 | N/A |
| F-score Threshold | 0.426 | N/A |
| F-score | 0.8993 | N/A |