smile	binding.affinity
[H]N([H])C1=C(C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(F)=C1[H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	1360
[H]N([H])C1=C(C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(F)=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1[H]	2130
[H]N([H])C1=C([H])C(F)=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC([H])=C([H])S1	67.11
[H]N([H])C1=C(C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(F)=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F	1870
[H]N([H])C1=C(C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(F)=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]	2530
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C3=C([H])N=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	1260
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(SC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]	4220
[H]OC(=O)C1=C([H])N=C(\C([H])=C(/[H])C2=C([H])C(SC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]	3200
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])C([H])=C1[H]	170
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	400
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C3=C([H])SC([H])=C3[H])=C2[H])C([H])=C1[H]	90
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])=C2[H])C([H])=C1[H]	1780
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)=C2[H])C([H])=C1[H]	100
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]	570
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	130
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)=C2[H])C([H])=C1[H]	910
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	290
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])C([H])=C1[H]	650
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)=C2[H])C([H])=C1[H]	90
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	420
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2[H])C([H])=C1[H]	1330
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]	20
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]	150
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]	3060
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C(=O)OC([H])([H])C([H])([H])[H]	760
[H]OC([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1N([H])[H]	1010
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C(F)(F)F	1815
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C(F)S1	70
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C(F)S1	140
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C(F)S1	1430
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C(F)S1	109.5
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C(S1)C([H])([H])[H]	580
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C([H])S1	570
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C([H])S1	6200
[H]N(C(=O)C(=C(/[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])\C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=NC([H])=C([H])S1	2300
[H]N(C(=O)C(=C(/[H])C1=C([H])C([H])=C([H])S1)\C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=NC([H])=C([H])S1	560
[H]N([H])C1=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	480
[H]N([H])C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	560
[H]N([H])C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	710
[H]N([H])C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	990
[H]N([H])C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	165
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	1470
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	280
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC([H])=NS1	305
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=NS1)C([H])([H])[H]	410
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC([H])=C([H])C([H])=C1[H]	715
[H]N(C(=O)C1=C([H])C(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	4400
[H]N(C(=O)C1=C([H])C(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1N([H])C([H])([H])[H])C1=NC(=C([H])S1)C([H])([H])[H]	715
[H]N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	4250
[H]N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	415
[H]N([H])C1=C([H])C([H])=C(OC2=C(F)C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	180
[H]N([H])C1=C([H])C([H])=C(OC2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	370
[H]N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	1050
[H]N([H])C1=C([H])C([H])=C(OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	265
[H]N([H])C1=C([H])C([H])=C(OC2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	320
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC([H])=C([H])S1	245
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])[H]	220
[H]N(C(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	5250
[H]N(C(=O)C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	6150
[H]N(C(=O)C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	3300
[H]N(C(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	9550
[H]N(C(=O)C1=C([H])C(OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	1345
[H]N(C(=O)C1=C([H])C(OC2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	3650
[H]N(C(=O)C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	6450
[H]N(C(=O)C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	2250
[H]N(C(=O)C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	1270
[H]N(C(=O)C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	855
[H]N(C(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	1020
[H]N(C(=O)C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	385
[H]N(C(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	595
[H]N(C(=O)C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	230
[H]N(C(=O)C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	9900
[H]N(C(=O)C1=C([H])C(OC2=C(F)C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	1425
[H]N(C(=O)C1=C([H])C(OC2=C([H])C(F)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	4250
[H]N(C(=O)C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	2010
[H]N([H])C1=C([H])C([H])=C(Cl)C([H])=C1C(=O)N([H])C1=NC([H])=C([H])S1	6800
[H]N([H])C1=C([H])C([H])=C(Cl)C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	3950
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1SC1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	250
[H]N(C(=O)C1=C([H])C(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1SC1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]	970
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1SC1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC([H])=C([H])S1	120
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC([H])=C([H])S1	76
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1F)C1=NC([H])=C([H])S1	57
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C(F)=C1[H])C1=NC([H])=C([H])S1	40
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])S1	38
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC([H])=C([H])S1	120
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=C([H])S1	160
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	160
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=NC([H])=C([H])S1	100
[H]N(C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	365
[H]N(C(=O)C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	115
[H]N([H])C([H])([H])[C@]([H])(OC1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1)C([H])([H])[H]	855
[H]O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])OC1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1	270
[H]OC([H])([H])C([H])([H])OC1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1	490
[H]OC([H])([H])[C@]([H])(OC1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1)C([H])([H])[H]	115
[H]N(C(=O)C1=C([H])C(O[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	245
[H]N(C(=O)C1=C([H])C(O[C@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	7300
[H]N(C(=O)C1=C([H])C(OC([H])(C([H])([H])OC([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	365
[H]N(C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	290
[H]N(C(=O)C1=C([H])C(O[C@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	130
[H]N(C(=O)C1=C([H])C(O[C@@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	125
[H]OC([H])([H])[C@]([H])(OC1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1)C([H])(C([H])([H])[H])C([H])([H])[H]	280
[H]OC([H])([H])[C@]([H])(OC1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1)C(F)(F)F	515
[H]OC([H])([H])C([H])([H])[C@]([H])(OC1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1)C([H])([H])[H]	105
[H]OC([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C([H])S1	500
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	5000
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C([H])=NC([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]	275
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	305
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	185
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])=C2N=C(N([H])C2=C1[H])C1=NC([H])=C([H])C([H])=C1[H]	815
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	370
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	205
[H]N(C1=NC(=C([H])S1)C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C12	565
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C([H])=C12	305
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(F)C([H])=C(F)C([H])=C3[H])C([H])=C12	180
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(F)C([H])=C([H])C([H])=C3F)C([H])=C12	60
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	90
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3Cl)S(=O)(=O)C([H])([H])[H])C([H])=C12	200
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])=C12	280
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C(C([H])=C3[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])=C12	2835
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C#N)C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])=C12	40
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=N3)C([H])=C12	1100
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C([H])N=C([H])C([H])=N3)C([H])=C12	3450
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C([H])C([H])=NC([H])=N3)C([H])=C12	8350
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(F)C([H])=C([H])C([H])=N3)C([H])=C12	190
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(Cl)C([H])=C([H])C([H])=N3)C([H])=C12	125
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(Br)C([H])=C([H])C([H])=N3)C([H])=C12	65
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=N3)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C12	7500
[H]OC([H])([H])C1=C(OC2=C([H])C([H])=C3N=C([H])N=C(N([H])C4=NN(C([H])=C4[H])C([H])([H])[H])C3=C2[H])N=C([H])C([H])=C1[H]	825
[H]N(C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	110
[H]N(C1=NN([H])C([H])=C1[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	80
[H]N(C1=NC(=NS1)C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	75
[H]N(C1=NN=C([H])C([H])=C1[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	4470
[H]N(C1=NC([H])=C([H])N=C1[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	320
[H]N(C1=NC([H])=C(N=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	175
[H]N(C1=NC([H])=C(Cl)N=C1[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12	3525
[H]N(C1=NC([H])=C([H])S1)C1=NC([H])=NC2=C([H])C([H])=C(SC3=NN=C([H])N3C([H])([H])[H])C([H])=C12	1155
[H]N(C1=NC(=C([H])S1)C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(SC3=NN=C([H])N3C([H])([H])[H])C([H])=C12	1510
[H]N(C1=NC(=C([H])S1)C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C([H])=C12	155
[H]N(C1=NC(=C([H])S1)C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(F)C([H])=C([H])C([H])=C3[H])C([H])=C12	100
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	200
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)N([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	5000
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])S1(=O)=O)C1=NC([H])=C([H])C([H])=C1[H]	275
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	190
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1=O)C1=NC([H])=C([H])C([H])=C1[H]	100
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)OC([H])([H])C1=O)C1=NC([H])=C([H])C([H])=C1[H]	55
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)N(C([H])([H])[H])C([H])([H])C1=O)C1=NC([H])=C([H])C([H])=C1[H]	120
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)OC([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	155
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])C1=NN=NN1C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	240
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	2400
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])C([H])([H])[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	2700
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3F)=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	3000
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C([H])C(=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	7400
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	9600
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(F)C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1100
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(F)C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	5470
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(F)C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	6100
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	630
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C([H])C(F)=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	930
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1100
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1100
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1500
[H]N([H])C(=O)C1=C([H])C([H])=C(OC2=C(C([H])=C3N([H])C(=NC3=C2[H])C2=NC([H])=C([H])C([H])=C2[H])[C@]2([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]	1600
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1700
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C([H])C(C#N)=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1900
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C#N)C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1900
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]	1900
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]	852.5
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C2[H])C([H])=C1[H]	37.5
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C([H])(C([H])([H])[H])C([H])([H])[H]	330
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]	2930
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]	724
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]	90.5
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]	1180
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=O)C([H])([H])S1	4680
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]	2860
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C(Br)S1)C([H])(C([H])([H])[H])C([H])([H])[H]	320
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC2=C(S1)C([H])([H])C([H])([H])C2([H])[H]	79
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C(S1)C([H])([H])[H])C([H])([H])[H]	2860
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C([H])(C([H])([H])[H])C([H])([H])[H]	91.5
[H]C([H])=C(C1=C([H])SC(=N1)N([H])C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]	158
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]	1040
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]	1300
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]	4100
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C(F)=C([H])C(F)=C3[H])=C2[H])C([H])=C1[H]	90
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])=C2[H])C([H])=C1[H]	40
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	70
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C(F)=C([H])C(F)=C3[H])=C2[H])C([H])=C1[H]	50
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(Cl)O3)=C2[H])C([H])=C1[H]	30
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])C([H])=C1[H]	90
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC([H])([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C2[H])C([H])=C1[H]	70
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC([H])([H])C(F)(F)C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	30
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC3([H])C([H])([H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])=C2[H])C([H])=C1[H]	100
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	210
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]	160
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])=C2[H])C([H])=C1[H]	40
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C2[H])C([H])=C1[H]	60
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C([H])C(Cl)=C3[H])=C2[H])C([H])=C1[H]	110
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2[H])C([H])=C1[H]	100
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C([H])C(F)=C3[H])=C2[H])C([H])=C1[H]	180
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C([H])C(=C3[H])N(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]	400
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])=C1[H]	60
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	60
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	110
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C(Cl)C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	70
[H]N(C(=O)[C@@]([H])(N1C([H])=C(Cl)C(=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=N1	140
[H]N(C(=O)[C@@]([H])(N1C([H])=C(C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	160
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	160
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	370
[H]N(C(=O)[C@@]([H])(N1C([H])=C(Cl)C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	260
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	260
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C(F)(F)F	330
[H]N(C(=O)[C@@]([H])(N1C([H])=C(C(=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	440
[H]N(C(=O)[C@@]([H])(N1C([H])=C(Cl)C(=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	480
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	510
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	560
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=N1	590
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1	600
[H]N([H])C1=C([H])C(F)=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]	620
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])S1	595
[H]N(C(=O)[C@@]([H])(N1C([H])=C(Cl)C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C(C([H])=N1)C([H])([H])[H]	700
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])C([H])=C1[H]	720
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	910
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=N1	1300
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])S1	1300
[H]N(C(=O)[C@@]([H])(C1=C([H])C(Cl)=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C(=O)C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=N1	1420
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	1500
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	1500
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	3300
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C(C([H])=N1)C([H])([H])[H]	3500
[H]N([H])C(=O)[C@@]1([H])[C@]2([H])C([H])=C([H])[C@@]([H])(C2([H])[H])[C@@]1([H])N([H])C1=NC(=NC([H])=C1Cl)N([H])C1=C([H])C([H])=C2C(=C1OC([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2([H])[H]	60
[H]N(C(=O)C1=C([H])C2=C(C([H])=C(O2)C([H])([H])[H])C(OC2=C([H])N=C(C([H])=N2)C(=O)N(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=NC([H])=C(N=C1[H])C([H])([H])[H]	216
[H]N(C(=O)C1=C([H])C2=C(C([H])=C(O2)C([H])([H])[H])C(OC2=C([H])N=C(N=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=NC([H])=C(N=C1[H])C([H])([H])[H]	188
[H]OC(=O)C([H])([H])N1N=C(N([H])C(=O)[C@@]([H])(N2C([H])=NC(=C2[H])C(F)(F)F)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]	1080
[H]OC(=O)C(=O)N([H])C1=C([H])C([H])=C(N=C1[H])N([H])C(=O)[C@@]([H])(N1C([H])=NC(=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	456
[H]N(C(=O)[C@@]([H])(N1C([H])=NC(=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=NN=NN1[H]	284
[H]OS(=O)(=O)C1=C([H])C([H])=C(N=C1[H])N([H])C(=O)[C@@]([H])(N1C([H])=NC(=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	2490
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(N=C1[H])N([H])C(=O)[C@@]([H])(N1C([H])=NC(=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	565
[H]OC(=O)C1=C([H])C([H])=C(N=C1[H])N([H])C(=O)[C@@]([H])(N1C([H])=NC(=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]	90
[H]N(C(=O)[C@@]([H])(N1C([H])=NC(=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]	114
[H]N(C(=O)C1=C([H])C(O[C@@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)OC([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	245
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC([H])=C([H])S1	28.3
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	297
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC([H])=C(F)S1	47.7
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C1=NC([H])=C([H])S1	48
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C1=NC([H])=C(F)S1	52
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1	62.6
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=C1[H])C1=NC([H])=C(F)S1	65.4
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C1[H])C1=NC([H])=C([H])S1	101
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C1[H])C1=NC([H])=C(F)S1	78
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])[C@]([H])(F)C2([H])[H])=C1[H])C1=NC([H])=C([H])S1	52.3
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])[C@]([H])(F)C2([H])[H])=C1[H])C1=NC([H])=C(F)S1	44.8
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C1=NC([H])=C([H])S1	90.4
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C1=NC([H])=C(F)S1	64.6
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]	250
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC(=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]	890
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC(=O)C([H])([H])S1	120
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H]	90.1
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=C([H])N=C(C([H])=N1)C([H])([H])[H]	165
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC([H])=C([H])N2C([H])=C([H])N=C12	1000
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H]	95.1
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H]	44.8
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	265
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H]	144
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	242
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])[C@]([H])(F)C2([H])[H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H]	63.1
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])[C@]([H])(F)C2([H])[H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	83.5
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H]	460
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]	491
[H]N([H])C1=C([H])N=C2N(C([H])=C([H])C([H])=C2C2=C(F)C([H])=C([H])C([H])=C2F)C1=O	4000
[H]N([H])C1=NN2C([H])=C(N=C([H])C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]	6000
CC1=CC(=CC(=O)N1[C@@H](CC1CCCC1)C(=O)NC1=NC=C(Cl)S1)S(=O)(=O)C1CC1	160
CC1=CC(=CC(=O)N1[C@@H](CC1CCCCO1)C(=O)NC1=NC=C(Cl)S1)S(=O)(=O)C1CC1	1200
CC1=CC(=CC(=O)N1[C@@H](CC1CCCC1)C(=O)NC1=NC=C(F)S1)S(=O)(=O)C1CC1	630
CC1=CC(=CC(=O)N1[C@@H](CC1CCCCO1)C(=O)NC1=NC=C(F)S1)S(=O)(=O)C1CCCC1	500
CC1=CC(=CC(=O)N1[C@@H](CC1CCCCO1)C(=O)NC1=NC=C(Cl)S1)S(=O)(=O)C1CCCC1	160
CCCCC(N1C(C)=CC(=CC1=O)S(=O)(=O)C1CCCC1)C(=O)NC1=NC=CS1	1600
CC1=CC(=CC(=O)N1C(CC1CCCCO1)C(=O)NC1=NC=CS1)S(=O)(=O)C1CCCC1	1000
CC1=CC(=CC(=O)N1C(CC1CCCC1)C(=O)NC1=NC=CS1)S(=O)(=O)C1CCCC1	139.5
CC(C)CC(N1C(C)=CC(=CC1=O)S(=O)(=O)C1CCCC1)C(=O)NC1=NC=CS1	790
CCS(=O)(=O)C1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(C)=C1	2000
CC1=CC(=CC(=O)N1[C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1)S(C)(=O)=O	6300
CC(C)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1	1000
O=C(NC1=NC=CS1)[C@H](CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)CC1=CC=CC=C1	400
O=C(NC1=NC=CS1)[C@H](CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)C1=CC=CO1	160
CC1=CC=C(C(F)=C1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1	250
CC1=CC=CC(=C1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1	200
FC1=CC(=CC(F)=C1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1	200
ClC1=CC=CC(=C1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1	310
CS(=O)(=O)N1CCN([C@@H](CC2CCCCO2)C(=O)NC2=NC=C(Cl)S2)C(=O)C1	2000
ClC1=CN=C(NC(=O)[C@H](CC2CCCCO2)N2CCN(CC2=O)S(=O)(=O)C2CC2)S1	790
O=C(NC1=NC=CS1)[C@H](CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)C1CCCC1	63
O=C(NC1=NC=CS1)C(CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)C1CC1	250
CS(=O)(=O)N1CCN(C(CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1	1600
O=C(NC1=NC=CS1)[C@H](CC1CCCC1)N1C=NC2=C(C=CC(=C2)S(=O)(=O)C2CC2)C1=O	2000
CCS(=O)(=O)C1=CC2=C(C=C1)C(=O)N(C=N2)[C@@H](CC1CCCCO1)C(=O)NC1=NC=C(F)S1	5000
CCS(=O)(=O)C1=CC2=C(C=C1)C(=O)N(C=N2)[C@@H](CC1CCCCC1)C(=O)NC1=NC=C(F)S1	630
ClC1=CN=C(NC(=O)[C@H](CC2CCCCC2)N2C=NC3=C(C=CC(=C3)S(=O)(=O)C3CCCC3)C2=O)S1	400
FC1=CN=C(NC(=O)[C@H](CC2CCCCC2)N2C=NC3=C(C=CC(=C3)S(=O)(=O)C3CCCC3)C2=O)S1	310
CNC(=O)C1=CC2=C(C=C1)C(=O)N(C=N2)[C@@H](CC1CCCCC1)C(=O)NC1=NC=C(Cl)S1	99.5
CC1=CC2=C(C=C1)N=CN([C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1)C2=O	2500
FC1=CC2=C(C=C1)N=CN([C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1)C2=O	4000
ClC1=CC2=C(C=C1)N=CN(C(CC1CCCCC1)C(=O)NC1=NC=CS1)C2=O	2000
ClC1=CN=C(NC(=O)C(CC2CCCCO2)N2C=NC3=C(C=CC(=C3)C(=O)NC3CC3)C2=O)S1	1200
CS(=O)(=O)C1=CC2=C(C=C1)C(=O)N(C=N2)[C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1	500
CS(=O)(=O)C1=CC2=C(C=C1)C(=O)N(C(CC1CCCCC1)C(=O)NC1=NC=C(Cl)S1)C(=O)N2	630
FC1=CC2=C(NC(=O)N([C@@H](CC3CCCCC3)C(=O)NC3=NC=CS3)C2=O)C=C1	3100
ClC1=CC2=C(C=C1)C(=O)N([C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1)C(=O)N2	2000
O=C(NC1=NC=CS1)[C@H](CC1CCCCC1)N1C(=O)NC2=C(C=CC=C2)C1=O	4000
CS(=O)(=O)C1=CC2=C(C=C1)C(=O)N([C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1)C(=O)N2	1000
COC[C@H](C)OC1=CC(CCC2=C(F)C=CC=C2F)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	77.5
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC=C2OC)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	83
COC[C@H](C)OC1=CC(\C=C\C2=CC(F)=CC(F)=C2F)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	778
COC[C@H](C)OC1=CC(\C=C\C2=C(F)C=CC=C2F)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	90
COC[C@H](C)OC1=CC(\C=C\C2=CC(F)=CC=C2F)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	134
COC[C@H](C)OC1=CC(\C=C\C2=CC=C(F)C=C2F)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	95
COC[C@H](C)OC1=CC(\C=C\C2=CC=C(F)C=C2)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	120
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC=C2F)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	56
COC[C@H](C)OC1=CC(\C=C\C2=CC=C(C=C2)[N+]([O-])=O)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	284
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC(=C2)[N+]([O-])=O)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	165
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC=C2[N+]([O-])=O)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O	296
COC[C@H](C)OC1=CC(CCC2=CC=CC=C2OC)=CC(=C1)C(=O)NC1=NN(C)C=C1	135
COC[C@H](C)OC1=CC(CCC2=CC(F)=CC(F)=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	855
COC[C@H](C)OC1=CC(CCC2=C(F)C=CC=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	131
COC[C@H](C)OC1=CC(CCC2=CC=C(F)C=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	184
COC[C@H](C)OC1=CC(CCC2=CC=C(F)C=C2)=CC(=C1)C(=O)NC1=NN(C)C=C1	216
COC[C@H](C)OC1=CC(CCC2=CC=CC=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	217
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC(C)=N2)=CC(=C1)C(=O)NC1=NN(C)C=C1	132
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC=C2OC)=CC(=C1)C(=O)NC1=NN(C)C=C1	115
COC[C@H](C)OC1=CC(\C=C\C2=CC(F)=CC(F)=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	848
COC[C@H](C)OC1=CC(\C=C\C2=C(F)C=CC=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	161
COC[C@H](C)OC1=CC(\C=C\C2=CC(F)=CC=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	200
COC[C@H](C)OC1=CC(\C=C\C2=CC=C(F)C=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	109
COC[C@H](C)OC1=CC(\C=C\C2=CC=C(F)C=C2)=CC(=C1)C(=O)NC1=NN(C)C=C1	119
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1	80
COC[C@H](C)OC1=CC(\C=C\C2=CC=C(C=C2)[N+]([O-])=O)=CC(=C1)C(=O)NC1=NN(C)C=C1	852
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC(=C2)[N+]([O-])=O)=CC(=C1)C(=O)NC1=NN(C)C=C1	239
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC=C2[N+]([O-])=O)=CC(=C1)C(=O)NC1=NN(C)C=C1	283
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])N([H])C3=NC([H])=C([H])C(=C23)C2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H]	340