TargetNet
P35462
D(3) dopamine receptor
Function
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
Database Links
| Database | Links |
|---|---|
| UniProt | P35462 |
| PDB | 3PBL |
| BioGrid | 108148 |
| BindingDB | P35462 |
| DrugBank | DB00714, DB01239, DB00907, DB01403, DB00334, DB00413, DB00268, DB00246 |
| Guide to PHARMACOLOGY | 216 |
| PharmGKB | PA27479 |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 1814 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9691 | 9.9669 × 10-4 |
| Accuracy | 0.9149 | 0.0017 |
| Sensitivity | 0.9235 | 0.0034 |
| Specificity | 0.9067 | 0.0023 |
| BEDROC | 0.9899 | 0.0012 |
| MCC Threshold | 0.556 | N/A |
| MCC | 0.8357 | N/A |
| F-score Threshold | 0.472 | N/A |
| F-score | 0.9173 | N/A |