TargetNet
P35351
Type-2 angiotensin II receptor
Function
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (By similarity).
Database Links
| Database | Links |
|---|---|
| UniProt | P35351 |
| PDB | 2G2A |
| BioGrid | Not available |
| BindingDB | P35351 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 35 |
| PharmGKB | Not available |
| KEGG | rno:24182 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 24182 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9886 | 0.0012 |
| Accuracy | 0.9487 | 0.0031 |
| Sensitivity | 0.9447 | 0.0045 |
| Specificity | 0.9525 | 0.0033 |
| BEDROC | 0.9992 | 1.6949 × 10-4 |
| MCC Threshold | 0.336 | N/A |
| MCC | 0.9118 | N/A |
| F-score Threshold | 0.336 | N/A |
| F-score | 0.9548 | N/A |