TargetNet
P34976
Type-1 angiotensin II receptor
Function
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P34976 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P34976 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | Not available |
| PharmGKB | Not available |
| KEGG | Not available |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 100009164 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9965 | 6.3027 × 10-4 |
| Accuracy | 0.9914 | 0.0036 |
| Sensitivity | 0.991 | 0.005 |
| Specificity | 0.9918 | 0.003 |
| BEDROC | 0.9999 | 6.8495 × 10-5 |
| MCC Threshold | 0.486 | N/A |
| MCC | 0.9884 | N/A |
| F-score Threshold | 0.486 | N/A |
| F-score | 0.9947 | N/A |