TargetNet
P34972
Cannabinoid receptor 2
Function
Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
Database Links
| Database | Links |
|---|---|
| UniProt | P34972 |
| PDB | 2KI9 |
| BioGrid | Not available |
| BindingDB | P34972 |
| DrugBank | DB00486 |
| Guide to PHARMACOLOGY | 57 |
| PharmGKB | PA26682 |
| KEGG | hsa:1269 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 1269 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9824 | 7.9781 × 10-4 |
| Accuracy | 0.946 | 0.002 |
| Sensitivity | 0.9408 | 0.002 |
| Specificity | 0.9507 | 0.0023 |
| BEDROC | 0.9955 | 6.4992 × 10-4 |
| MCC Threshold | 0.49 | N/A |
| MCC | 0.894 | N/A |
| F-score Threshold | 0.458 | N/A |
| F-score | 0.9446 | N/A |