TargetNet
P33765
Adenosine receptor A3
Function
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.
Database Links
| Database | Links |
|---|---|
| UniProt | P33765 |
| PDB | 1OEA, 1R7N |
| BioGrid | 106650 |
| BindingDB | P33765 |
| DrugBank | DB00640, DB01223 |
| Guide to PHARMACOLOGY | 21 |
| PharmGKB | PA24589 |
| KEGG | hsa:140 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 140 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9825 | 6.8305 × 10-4 |
| Accuracy | 0.9554 | 0.0015 |
| Sensitivity | 0.9494 | 0.0031 |
| Specificity | 0.9617 | 0.0016 |
| BEDROC | 0.9964 | 0.0017 |
| MCC Threshold | 0.466 | N/A |
| MCC | 0.9104 | N/A |
| F-score Threshold | 0.466 | N/A |
| F-score | 0.9562 | N/A |