TargetNet
P32745
Somatostatin receptor type 3
Function
Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Database Links
| Database | Links |
|---|---|
| UniProt | P32745 |
| PDB | Not available |
| BioGrid | 112631 |
| BindingDB | P32745 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 357 |
| PharmGKB | PA36156 |
| KEGG | hsa:6753 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 6753 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9941 | 0.001 |
| Accuracy | 0.9678 | 0.002 |
| Sensitivity | 0.9699 | 0.0026 |
| Specificity | 0.966 | 0.0025 |
| BEDROC | 0.9974 | 0.003 |
| MCC Threshold | 0.382 | N/A |
| MCC | 0.9427 | N/A |
| F-score Threshold | 0.382 | N/A |
| F-score | 0.9691 | N/A |