TargetNet
P32247
Bombesin receptor subtype-3
Function
Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Database Links
| Database | Links |
|---|---|
| UniProt | P32247 |
| PDB | Not available |
| BioGrid | Not available |
| BindingDB | P32247 |
| DrugBank | Not available |
| Guide to PHARMACOLOGY | 40 |
| PharmGKB | PA25427 |
| KEGG | hsa:680 |
| BioCyc | Not available |
| Entrez Gene (GeneID) | 680 |
Chemical Space of the Positive Compounds
Model Performance Metrics
| Metric | Mean Value | Standard Deviation |
|---|---|---|
| AUC | 0.9604 | 0.0077 |
| Accuracy | 0.9061 | 0.0068 |
| Sensitivity | 0.9251 | 0.0087 |
| Specificity | 0.8829 | 0.0085 |
| BEDROC | 0.9936 | 0.0123 |
| MCC Threshold | 0.682 | N/A |
| MCC | 0.8284 | N/A |
| F-score Threshold | 0.528 | N/A |
| F-score | 0.9223 | N/A |