Sodium-dependent serotonin transporter
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner (By similarity).
Database | Links |
---|---|
UniProt | P31652 |
PDB | Not available |
BioGrid | Not available |
BindingDB | P31652 |
DrugBank | Not available |
Guide to PHARMACOLOGY | Not available |
PharmGKB | Not available |
KEGG | rno:25553 |
BioCyc | Not available |
Entrez Gene (GeneID) | 25553 |
Metric | Mean Value | Standard Deviation |
---|---|---|
AUC | 0.9844 | 5.8329 × 10-4 |
Accuracy | 0.945 | 7.7133 × 10-4 |
Sensitivity | 0.96 | 0.0015 |
Specificity | 0.9294 | 0.0013 |
BEDROC | 0.9975 | 0.0015 |
MCC Threshold | 0.482 | N/A |
MCC | 0.8908 | N/A |
F-score Threshold | 0.482 | N/A |
F-score | 0.947 | N/A |